Preserving subject variability in group fMRI analysis: performance evaluation of GICA vs. IVA

Frontiers in Systems Neuroscience
Andrew M MichaelVince D Calhoun

Abstract

Independent component analysis (ICA) is a widely applied technique to derive functionally connected brain networks from fMRI data. Group ICA (GICA) and Independent Vector Analysis (IVA) are extensions of ICA that enable users to perform group fMRI analyses; however a full comparison of the performance limits of GICA and IVA has not been investigated. Recent interest in resting state fMRI data with potentially higher degree of subject variability makes the evaluation of the above techniques important. In this paper we compare component estimation accuracies of GICA and an improved version of IVA using simulated fMRI datasets. We systematically change the degree of inter-subject spatial variability of components and evaluate estimation accuracy over all spatial maps (SMs) and time courses (TCs) of the decomposition. Our results indicate the following: (1) at low levels of SM variability or when just one SM is varied, both GICA and IVA perform well, (2) at higher levels of SM variability or when more than one SMs are varied, IVA continues to perform well but GICA yields SM estimates that are composites of other SMs with errors in TCs, (3) both GICA and IVA remove spatial correlations of overlapping SMs and introduce artificial cor...Continue Reading

References

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Mar 29, 2011·Frontiers in Systems Neuroscience·Elena A AllenVince D Calhoun
Nov 24, 2011·Frontiers in Systems Neuroscience·Siddharth KhullarVince D Calhoun

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Citations

Apr 22, 2015·NeuroImage·Joanne R HaleAndrew P Bagshaw
Jul 16, 2016·Human Brain Mapping·Ryan L MuetzelTonya White
Mar 10, 2017·PloS One·Shaojie ChenBrian S Caffo
Mar 14, 2017·IEEE Transactions on Medical Imaging·Yuri Levin-SchwartzTulay Adali
Nov 16, 2016·Reviews in the Neurosciences·Golrokh Mirzaei, Hojjat Adeli
Jun 6, 2017·Frontiers in Neuroscience·Yuhui DuVince D Calhoun
Apr 12, 2019·Frontiers in Aging Neuroscience·Yang HuZhi Yang
Jan 8, 2021·Acta Neuropathologica Communications·Xuan Vinh To, Fatima A Nasrallah
Oct 8, 2017·Neuroimaging Clinics of North America·Vince D Calhoun, Nina de Lacy
Aug 10, 2021·Cognitive Neurodynamics·Ioannis K GallosConstantinos I Siettos

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Methods Mentioned

BETA
PCA

Software Mentioned

GIFT
GICA
MATLAB
GLM
IVA
SimTB

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