PMID: 2495904May 1, 1989Paper

Pressure control inverse ratio ventilation as a method to reduce peak inspiratory pressure and provide adequate ventilation and oxygenation

Chest
D C LainD Causey

Abstract

Nineteen patients with ARDS or pneumonia who were ventilated with PcIRV on the Siemens-Elema Servo 900 C were retrospectively reviewed. The PcIRV reduced peak airway pressure, PEEP, increased Paw, and improved ventilation and oxygenation in these patients. When these patients were compared with themselves on prior conventional IPPV, all had a decrease in PIP, an increase in Paw and most had a decrease in VE, with no change in PaCO2 and an increase in PaO2. The increase in Paw may have contributed to this improved arterial oxygenation. High levels of PIP and PEEP during IPPV have been identified as risk factors in the development of barotrauma and residual parenchymal pulmonary damage. We propose that PcIRV allows for adequate ventilation and oxygenation with decreases in PIP, extrinsically added PEEP and inspired O2 concentration. This mode of ventilation may decrease the morbidity associated with IPPV utilizing high PIP and PEEP.

References

Nov 1, 1978·Archives of Disease in Childhood·F P ManginelloP A Auld
Apr 1, 1975·Archives of Surgery·W G Horton, F W Cheney
Jul 1, 1974·Archives of Disease in Childhood·E O Reynolds, A Taghizadeh
Mar 1, 1973·Radiology·D R Dyck, C J Zylak
Jun 1, 1982·Critical Care Medicine·F P PrimianoM D Lough

❮ Previous
Next ❯

Citations

May 1, 1996·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·M R Lessard
May 1, 1996·Disease-a-month : DM·D P Schuster, M H Kollef
Oct 6, 2000·Clinics in Chest Medicine·R G Brower, H E Fessler
Jul 1, 1997·Critical Care Clinics·R C Sachdeva, K K Guntupalli
Apr 29, 1998·Journal of Critical Care·P B RichR H Bartlett
Jan 5, 1995·The New England Journal of Medicine·M H Kollef, D P Schuster
Feb 15, 2001·Critical Care Medicine·A MercatC Richard
May 1, 1993·Acta Anaesthesiologica Scandinavica·P Valta, J Takala
Jan 1, 1997·Acta Anaesthesiologica Scandinavica·U LudwigsG Hedenstierna
Nov 10, 1990·BMJ : British Medical Journal·J S TurnerM A Branthwaite
Nov 20, 1993·BMJ : British Medical Journal·R BealeD Bihari
Aug 10, 2000·American Journal of Respiratory and Critical Care Medicine·N RossiA Pesenti
Jan 1, 1990·Intensive Care Medicine·K G Hickling
Nov 22, 2000·The Journal of Trauma·P B RichR B Hirschl
Sep 1, 1993·Chest·P B BlanchN Camner
Dec 9, 1994·Clinical Intensive Care : International Journal of Critical & Coronary Care Medicine·J O Auler JúniorR V do Amaral
Oct 10, 2001·Chest·R G BrowerM A Matthay
Sep 22, 1998·Chest·J YanosJ Verhey
May 6, 2010·Chest·Adebayo EsanCurtis N Sessler
Nov 1, 1991·Chest·C S Sassoon
Dec 1, 1992·Chest·D H Fiser, W M Walker
Feb 19, 2013·Medicina intensiva·M Delgado Martín, R Fernández Fernández
Aug 1, 1995·Chest·L D Hudson
Dec 1, 1992·Journal of Cardiothoracic and Vascular Anesthesia·B A ShapiroW T Peruzzi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.