PMID: 1200156Nov 1, 1975Paper

Pressure dependence of the mechanical properties of arteries in vivo

The American Journal of Physiology
R H Cox

Abstract

Simultaneously measurements of intra-arterial pressure and external diameter were recorded from the thoracic and abdominal aortas, the carotid, brachiocephalic, left subclavian, and femoral arteries of anesthetized dogs. Data were recorded under control conditions and during efferent vagal stimulation, and were used to compute values of wall geometry, mechanical properties, phase velocity, and characteristic impedance. Values of these parameters computed for both control and vagal stimulation were used to represent their dependence on mean arterial pressure. Both the dynamic elastic modulus and the phase velocity increased with mean pressure at each arterial site. Values of computed characteristic impedance were constant and independent of mean arterial pressure between 80--150 mmHg. The tropical application of norepinephrine (100 mug/ml) to the femoral artery produced no change in mean pressure, while external diameter and dynamic modulus were decreased, and characteristic impedance was increased. These results provide direct support for the conclusion of previous studies on vascular impedance spectra which suggested a constancy of characteristic impedance with changes in mean arterial pressure.

Citations

Jul 1, 1979·Pflügers Archiv : European journal of physiology·R D BauerE Wetterer
Jan 1, 1981·European Journal of Applied Physiology and Occupational Physiology·A BardouR Saumont
Mar 20, 2020·Arteriosclerosis, Thrombosis, and Vascular Biology·Shikai Yu, Carmel M McEniery
Jan 1, 1986·Acta Medica Scandinavica. Supplementum·E G Lakatta
Jan 1, 1989·Circulation·D H Blankenhorn, D M Kramsch
Sep 18, 2002·American Journal of Physiology. Heart and Circulatory Physiology·Silvia G LageMark A Creager
May 1, 1985·Circulation Research·B J Gentile, D R Gross
Nov 18, 2015·Journal of Hypertension·Tommy Y CaiUNKNOWN Childhood Asthma Prevention Study Team
Jul 1, 1994·Medical & Biological Engineering & Computing·D ManorR Beyar
Nov 29, 2001·Journal of Hypertension·C D GatzkaUNKNOWN ANBO2 investigators. Australian Comparative Outcome Trial of Angiotensin-Converting Enzyme Inhibitor- and Diuretic-Based Tre
Feb 20, 2015·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Rie SugawaraTakeharu Honda
Jan 1, 1990·Annals of Biomedical Engineering·P SipkemaD M Slife
Dec 20, 2011·Journal of Biomechanics·Takeo Matsumoto, Kazuaki Nagayama

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.