Pressure driven spinning: A multifaceted approach for preparing nanoscaled functionalized fibers, scaffolds, and membranes with advanced materials.

Biomicrofluidics
Suwan N Jayasinghe, Nicolai Suter

Abstract

Electrospinning, a flexible jet-based fiber, scaffold, and membrane fabrication approach, has been elucidated as having significance to the heath sciences. Its capabilities have been most impressive as it possesses the ability to spin composite fibers ranging from the nanometer to the micrometer scale. Nonetheless, electrospinning has limitations and hazards, negating its wider exploration, for example, the inability to handle highly conducting suspensions, to its hazardous high voltage. Hence, to date electrospinning has undergone an exhaustive research regime to a point of cliché. Thus, in the work reported herein we unveil a competing technique to electrospinning, which has overcome the above limitations and hazards yet comparable in capabilities. The fiber preparation approach unearthed herein is referred to as "pressure driven spinning (PDS)." The driving mechanism exploited in this fiber spinning process is the pressurized by-pass flow. This mechanism allows the drawing of either micro- or nanosized fibers while processing polymeric suspensions containing a wide range of advanced materials spanning structural, functional, and biological entities. Similar to electrospinning if the collection time of these continuous formed...Continue Reading

References

Feb 14, 2006·The Journal of Physical Chemistry. B·S N Jayasinghe, A C Sullivan
Jun 23, 2007·Angewandte Chemie·Andreas Greiner, Joachim H Wendorff
May 7, 2008·Biomedical Materials·Albert KwokSuwan N Jayasinghe
Aug 12, 2008·Biomedical Materials·Suwan N Jayasinghe
Aug 21, 2009·Biomicrofluidics·Yasmin SrivastavaTodd Thorsen
Dec 22, 2009·Integrative Biology : Quantitative Biosciences From Nano to Macro·Anil AbeyewickremeSuwan N Jayasinghe

❮ Previous
Next ❯

Citations

Dec 1, 2012·Biotechnology Advances·Ali TamayolDavid Juncker
Feb 11, 2014·Drug Discovery Today·Yu Long HanFeng Xu
Sep 21, 2011·Biotechnology Journal·Piergiorgio GentileGianluca Ciardelli
Nov 28, 2012·Advanced Healthcare Materials·Denis PonceletSuwan N Jayasinghe
Apr 18, 2014·Advanced Materials·Nasim AnnabiAli Khademhosseini
Sep 17, 2020·ACS Applied Materials & Interfaces·Danilo M Dos SantosLuiz H C Mattoso

❮ Previous
Next ❯

Methods Mentioned

BETA
flow cytometry
scanning
transmission electron microscopy
activated
scanning electron microscopy
fluorescence microscopy
chip

Software Mentioned

FACScan
SUMMIT

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.