PMID: 9192281Mar 1, 1997Paper

Presynaptic terminals in hyaline cells of normal and overstimulated chick inner ears

Journal of Neurocytology
J C FrisanchoY Raphael

Abstract

Hyaline cells are non-sensory epithelial cells of the vibrating part of the basilar membrane of chicks; they receive an extensive efferent innervation. Although these anatomical features suggest roles in auditory transduction, very little is known about the function of these cells. One possible way to understand function is by lesion experiments. We used synapsin-specific antibodies to study changes that occur in the pattern of efferent innervation in hyaline cells after lesion of the sensory epithelium induced by acoustic overstimulation. We found only small changes in hyaline cells after such trauma. These included a small increase in size and a small decrease in density of nerve terminals on hyaline cells. This suggests that hyaline cells and their nerve terminals are less susceptible to acoustic trauma than hair cells. Using neurofilament-specific antibodies we found little or no trauma-induced change in the density of nerve fibres that cross the basilar papilla and reach the hyaline cell region. This finding suggested that trauma to the hair cells does not necessarily lead to changes in the efferent fibres that cross the papilla and extend into the hyaline cell region. Using the trauma and the morphological parameters stud...Continue Reading

Citations

Sep 27, 2018·Cold Spring Harbor Perspectives in Medicine·Amanda S Janesick, Stefan Heller
May 2, 2001·The Journal of Comparative Neurology·R J GoodyearG P Richardson

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