Preteen insulin levels interact with caloric intake to predict increases in obesity at ages 18 to 19 years: a 10-year prospective study of black and white girls.

Metabolism: Clinical and Experimental
J A MorrisonPing Wang

Abstract

We evaluated the associations of teenage insulin and adolescent diet with 10-year weight gain in an analysis sample of black and white girls matched for pubertal stage, body mass index (BMI) (or fat mass), and insulin at ages 9 to 10 years. We hypothesized that preteen insulin and insulin resistance would interact with dietary factors to positively predict increases in BMI. Furthermore, we hypothesized that increased insulin and insulin resistance, interacting with higher caloric intake during adolescence, would lead to greater increments in BMI in black girls than in white girls. Prospective 10-year follow-up was performed on 215 pairs of black and white schoolgirls matched at baseline by BMI (or fat mass), insulin, and pubertal stage, with repeated measures of body habitus, insulin, and dietary intake. When matched for BMI, black girls had higher fat-free mass and white girls had higher fat mass at ages 9 to 10 years. Black-white differences in caloric intake were not significant at ages 9 to 10 years, but black girls consumed more calories at age 19 years. Black girls consumed a greater percentage of calories from fat throughout. At age 19 years, black girls had higher BMI, fat mass index, and insulin. When matched at ages 9...Continue Reading

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Citations

May 19, 2011·International Journal of Obesity : Journal of the International Association for the Study of Obesity·I LabayenM Sjostrom
Oct 4, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Hiroto InabaWing Leung
Nov 3, 2010·The Journal of Pediatrics·Charles J Glueck, John A Morrison
Feb 16, 2018·The Cochrane Database of Systematic Reviews·Celeste E NaudeAnel Schoonees
Jul 6, 2018·The Cochrane Database of Systematic Reviews·Celeste E NaudeAnel Schoonees
Dec 14, 2018·BMC Medicine·Hubert KolbStephan Martin

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