Preterm and term labour in multiple pregnancies

Seminars in Fetal & Neonatal Medicine
Sarah Stock, Jane Norman

Abstract

The association between multiple pregnancy and preterm labour is well-established, with >50% of multiple births delivering before 37 weeks. However, there remains limited understanding of the factors predisposing to early delivery of twins. Physiological stimuli to the onset of parturition, including stretch, placental corticotrophin-releasing hormone and lung maturity factors, may be stronger in multiple pregnancies due to the increased fetal and placental mass. Pathological processes including infection and cervical insufficiency also have a role. Treatments that prevent preterm birth in singleton pregnancies, such as progesterone and cervical cerclage appear to be ineffective in multiple pregnancies. This article reviews aspects of preterm birth in twins and higher order multiples including epidemiology, prediction and prevention of preterm labour and potential mechanisms controlling onset of parturition. Evidence relating to the management of labour in preterm and term multiples is also discussed.

References

Feb 15, 1984·American Journal of Obstetrics and Gynecology·K J LevenoR Trubey
Nov 1, 1994·European Journal of Obstetrics, Gynecology, and Reproductive Biology·R GabrielP Wahl
Apr 1, 1995·Obstetrics and Gynecology·M O GardnerR L Copper
Aug 1, 1996·Acta Obstetricia Et Gynecologica Scandinavica·M MazorJ R Leiberman
Jan 12, 2000·Gynecologic and Obstetric Investigation·S SuzukiT Araki
Sep 11, 2002·Regulatory Peptides·Roger SmithShaun McGrath
Oct 10, 2002·American Journal of Physiology. Cell Physiology·Alexandra D OldenhofStephen J Lye
Aug 28, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·H HonestK S Khan
Jan 8, 2004·American Journal of Obstetrics and Gynecology·Jodie M DoddAnnabelle Chan
Mar 27, 2004·Proceedings of the National Academy of Sciences of the United States of America·Jennifer C CondonCarole R Mendelson
May 4, 2004·Journal of the Society for Gynecologic Investigation·Sam Mesiano
May 6, 2004·American Journal of Physiology. Endocrinology and Metabolism·Jennifer A MitchellStephen J Lye
Oct 2, 2004·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists Committee on Practice Bulletins-ObstetricsUNKNOWN ACOG Joint Editorial Committee
Oct 7, 2004·American Journal of Obstetrics and Gynecology·Thomas J GariteJames A Thorp
Oct 21, 2004·The Journal of Clinical Endocrinology and Metabolism·Vasso TerzidouMark R Johnson
Jul 16, 2005·American Journal of Obstetrics and Gynecology·Sarah McDonaldArne Ohlsson
Jul 28, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·Gordon C S SmithRichard Dobbie
Sep 15, 2005·American Journal of Obstetrics and Gynecology·Cande V AnanthAnthony M Vintzileos
Nov 3, 2005·Reproduction : the Official Journal of the Society for the Study of Fertility·Tamsin M Lindström, Phillip R Bennett
Dec 20, 2005·Seminars in Perinatology·Errol R NorwitzJoong Shin Park
Jan 9, 2007·BJOG : an International Journal of Obstetrics and Gynaecology·R RomeroM Mazor
Feb 19, 2008·American Journal of Obstetrics and Gynecology·Anna K SfakianakiCatalin S Buhimschi
Mar 5, 2009·The Journal of Clinical Endocrinology and Metabolism·Roger SmithDavid W Smith
Mar 14, 2009·Molecular Endocrinology·Carole R Mendelson
Mar 24, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Peter TurtonSusan Wray
Mar 26, 2009·American Journal of Obstetrics and Gynecology·Alan M PeacemanJoe Feinglass

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Citations

Dec 24, 2013·Best Practice & Research. Clinical Obstetrics & Gynaecology·George Makrydimas, Alexandros Sotiriadis
Aug 12, 2014·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Katarzyna Kosinska-KaczynskaMirosław Wielgos
Nov 14, 2014·Science Translational Medicine·Craig E RubensCourtney Gravett
Jul 13, 2012·Human Reproduction·E GroeneveldUNKNOWN OMEGA-project group
Aug 30, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Rocio RevelloIgnacio Zapardiel
Sep 16, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Amit KostoEyal Sheiner
Oct 3, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Rania OkbyEyal Sheiner
Jan 23, 2016·Seminars in Fetal & Neonatal Medicine·F Fuchs, M-V Senat
Mar 14, 2012·Seminars in Fetal & Neonatal Medicine·P C McParland
Dec 28, 2011·Reproductive Toxicology·P Yazdani BrojeniG Koren
Feb 26, 2011·Acta Paediatrica·R RizzoP Curatolo
Dec 10, 2013·Experimental Physiology·Sarah ArrowsmithSusan Wray
Jun 4, 2014·The Journal of Obstetrics and Gynaecology Research·Liang-Kai WangChie-Pein Chen
Oct 15, 2013·Experimental Physiology·Kathleen G Morgan
Jun 4, 2014·Journal of Neuroendocrinology·S Arrowsmith, S Wray
Mar 29, 2013·The Annals of Pharmacotherapy·Vanessa M SchmouderPatty Fan-Havard
Aug 3, 2017·The Journal of Endocrinology·Natasha SinghMark R Johnson
Aug 21, 2020·BMJ : British Medical Journal·Casey CrumpKristina Sundquist
Jun 30, 2018·Microbiome·Aline C FreitasUNKNOWN VOGUE Research Group
Jan 3, 2018·The Journal of Clinical Endocrinology and Metabolism·Irving L M H AyeGordon C S Smith
Jul 17, 2018·The Obstetrician & Gynaecologist : the Journal for Continuing Professional Development From the Royal College of Obstetricians & Gynaecologists·Sarah R MurrayJane E Norman
Oct 12, 2020·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Elina YlilehtoJukka Uotila
Feb 7, 2020·American Journal of Obstetrics and Gynecology·Agustin Conde-AgudeloKypros H Nicolaides
Mar 12, 2021·International Journal of Epidemiology·Casey CrumpKristina Sundquist
Apr 6, 2021·JAMA Pediatrics·Casey CrumpKristina Sundquist
Apr 10, 2021·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sonia T AnandKelli K Ryckman
May 5, 2021·American Journal of Perinatology·Clara WardYvonne W Cheng
Oct 14, 2021·JAMA Cardiology·Casey CrumpKristina Sundquist

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