Preterm premature rupture of membranes (PPROM): outcomes of delivery at 32(°/7)-33(6/7) weeks after confirmed fetal lung maturity (FLM) versus expectant management until 34(°/7) weeks

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Akila SubramaniamLuisa L Wetta

Abstract

Our objective was to compare maternal and neonatal outcomes in patients with preterm premature rupture of membranes (PPROM) delivered prior to 34(°/7) weeks upon confirmation of fetal lung maturity (FLM) to those managed expectantly until 34(°/7) weeks. We performed a retrospective cohort study of non-anomalous singleton gestations with PPROM occurring after 24 weeks delivered between 32(°/7) and 34(°/7) weeks from 2004 to 2012. Patients delivered upon documented FLM (+FLM)--defined as the presence of phosphatidylglycerol (PG) at 32(°/7)-33(6/7) weeks if amniotic fluid was obtainable vaginally--were compared with patients delivered without documented FLM between 32(°/7) and 34(°/7) weeks (expectant). Primary outcomes included maternal infection (clinically diagnosed endometritis or chorioamnionitis), placental abruption and a composite of neonatal morbidities (including but not limited to mechanical ventilation, intraventricular hemorrhage, necrotizing enterocolitis, sepsis and respiratory distress syndrome). Statistical analysis was performed using Student's t-test for continuous variables and Chi-square or Fisher's exact test for categorical data. Covariates were analyzed via multivariate logistic regression and adjusted odds...Continue Reading

References

Sep 1, 1986·American Journal of Obstetrics and Gynecology·S N Beydoun, S Y Yasin
Feb 18, 1998·American Journal of Obstetrics and Gynecology·R W NaefJ C Morrison
May 29, 2004·American Journal of Obstetrics and Gynecology·Andrew J HealyUNKNOWN Society of Maternal-Fetal Medicine
Dec 31, 2004·Obstetrics and Gynecology·Joelle M LiemanPatrick S Ramsey
Nov 26, 2010·Obstetrics and Gynecology·Elizabeth BatesAlan T N Tita
Dec 21, 2010·Database : the Journal of Biological Databases and Curation·Shabana VohraPhilip C Biggin
Dec 25, 2010·Database : the Journal of Biological Databases and Curation·Andrei L TurinskyShoshana J Wodak
Apr 22, 2011·Clinical Obstetrics and Gynecology·Thaddeus P Waters, Brian Mercer
Aug 21, 2012·American Journal of Obstetrics and Gynecology·David P van der HamJan G Nijhuis

❮ Previous
Next ❯

Citations

Dec 17, 2016·BJOG : an International Journal of Obstetrics and Gynaecology·A B Caughey

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Atalay EkinMehmet Ozeren
Journal of Perinatology : Official Journal of the California Perinatal Association
Sandy J FalkEllice Lieberman
© 2021 Meta ULC. All rights reserved