Pretreatment attrition and childhood social phobia: Parental concerns about medication

Journal of Anxiety Disorders
Brennan J YoungSusannah C Coaston

Abstract

Pretreatment attrition, the systematic self-exclusion of potential participants during the recruitment phase of a study, poses a significant threat to the external validity of randomized clinical trials. Very little is known about the factors that contribute to pretreatment attrition, especially among families seeking treatment for a child. The current study assessed pretreatment attrition in a randomized clinical trial of behavior therapy, fluoxetine, and placebo for child and adolescent social phobia. Reluctance toward medication treatment accounted for 44.7% of study refusals and was disproportionately common among ethnic minority families. Parents were particularly worried about the potential for side effects or physical/psychological dependency upon the medication. Results are discussed in terms of the implications for external validity in future psychopharmacological clinical trials.

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Citations

Oct 23, 2012·Journal of Child and Adolescent Psychopharmacology·Daniel AlmirallSusan A Murphy
Oct 12, 2012·Journal of Multidisciplinary Healthcare·Pernille PedersenHans Jørgen Søgaard
Sep 29, 2011·Patient Preference and Adherence·Lívia Santana, Leonardo F Fontenelle
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May 20, 2015·Journal of Clinical Child and Adolescent Psychology : the Official Journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53·Jeremy W PettitJames Jaccard
May 1, 2018·Child and Adolescent Mental Health·Michael J CrowleyLinda C Mayes
Nov 17, 2020·The Cochrane Database of Systematic Reviews·Anthony C JamesCathy Creswell

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