PMID: 9167755Jun 1, 1997Paper

Pretreatment characteristics of carcinoid tumors of the lung which predict aggressive behavior

American Journal of Clinical Oncology
P PerkinsJ D Cox

Abstract

Carcinoid tumors of the lung are uncommon and usually have a favorable outcome after resection. However, some patients have aggressive tumors that cannot be completely resected or have unfavorable outcomes after resection. A retrospective study was conducted to identify factors that predict outcome. Records of all previously untreated patients treated at the University of Texas M. D. Anderson Cancer Center (UTMDACC) between 1959 and 1994, with histologically confirmed carcinoid tumors of the lung, were reviewed. Histologic specimens were reclassified by contemporary criteria. Five-year survival for 79 patients without distant metastasis who had tumors with clinically aggressive features at diagnosis (defined as extension to the carina, involvement of regional lymph nodes, and/or vascular invasion) was 50.9% as compared with 76.9% (p = 0.01) for patients without these features. Five-year survival was 38.7% for patients with "atypical" histopathology (p = 0.01). Patients with aggressive tumors were more likely to have atypical tumors [odds ratio (OR) 11.73, p < 0.001]. However, 17.5% of the patients with clinically aggressive carcinoid tumors had tumors that were classified as typical. Carcinoid tumors of the lung that exhibit ag...Continue Reading

References

Jul 1, 1989·Respiratory Medicine·M TorreP Belloni
Jan 1, 1989·Scandinavian Journal of Thoracic and Cardiovascular Surgery·J G HallgrímssonJ H Jóhannsson
Mar 1, 1989·The Annals of Thoracic Surgery·F ReaF Sartori

❮ Previous
Next ❯

Citations

Sep 21, 2000·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·A CarrettaP Zannini
Feb 18, 1999·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·M MusiG Virotta
Dec 31, 2002·International Journal of Radiation Oncology, Biology, Physics·Bunyamin KaplanRitsuko Komaki
Aug 5, 2000·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·M K FergusonA P Yim
May 11, 2010·Medizinische Klinik·Claudia BöttgerBerend Isermann
Feb 7, 2001·Chest·W A CooperJ I Miller
Mar 13, 2010·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Tiago Noguchi MachucaJosé Jesus Camargo
Mar 22, 2015·Endocrine·Marco VolanteMauro Papotti
Sep 13, 2002·Chest·Michael D BrundageWilliam J Mackillop
Dec 23, 2006·Seminars in Thoracic and Cardiovascular Surgery·William H WarrenPaolo Gattuso
May 9, 2012·Clinical Medicine Insights. Case Reports·Stavros TryfonGaryfallos Alexandros
Jun 24, 2003·Clinical Nuclear Medicine·Stefano FantiNino Monetti
May 2, 2019·Journal of Medical Case Reports·Mohammed Z ShariffMohammad A Hossain
Mar 15, 2013·Clinical Nuclear Medicine·William MooreThomas V Bilfinger

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved