Prevalence and antimicrobial resistance pattern of multidrug-resistant enterococci isolated from clinical specimens

Indian Journal of Medical Microbiology
M M Salem-BekhitH M Hefni

Abstract

Vancomycin-resistant enterococci (VRE) pose an emerging problem in hospitals worldwide. The present study was undertaken to determine the occurrence, species prevalence, antibacterial resistance, and phenotypic and genetic characteristics of VRE isolated in Riyadh hospitals, KSA. Two hundred and six isolates of enterococcal species were obtained from clinical samples. The antibiotic susceptibility of isolates and minimum inhibitory concentration (MIC) tests for vancomycin and teicoplanin were determined. Molecular typing of VRE isolates was carried out by using pulsed field gel electrophoresis (PFGE) and the resistance genotype was determined by polymerase chain reaction (PCR). VRE accounted for 3.9% of the isolates and were detected mostly in urine, wound and blood specimens isolated from ICU, internal medicine and surgical wards. All strains were identified to species level and were found to consist of E. faecalis (69.2%), E. faecium (11.3%), E. avium (2.1%), E. hirae (0.8%), E. casseliflavus (1.3%) and E. gallinarum (1.3%) species. According to the susceptibility data obtained, 8 (3.9%) out of 206 isolates were found to be VRE (MICs > 32 μg/ml). The vanA, vanB and vanC gene fragments of E. faecalis, E. faecium and E. gallina...Continue Reading

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Citations

Mar 26, 2014·International Journal of Environmental Research and Public Health·Wei JiaWen Wang
Aug 18, 2016·Journal of Global Antimicrobial Resistance·Nadjette BourafaJean-Marc Rolain
Jun 1, 2016·The Indian Journal of Medical Research·Chimanjita PhukanKandarpa K Saikia
Feb 1, 2017·Chinese Medical Journal·Fawzia E Alotaibi, Elham E Bukhari
Jun 29, 2016·Journal of Chemotherapy·Mohammad Z AbdelkareemSayed F Abdelwahab
Oct 17, 2018·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Mohammad Abdallah, Mohammad Al-Saafin
Apr 4, 2019·Interdisciplinary Perspectives on Infectious Diseases·Sridevi Shridhar, Biranthabail Dhanashree
Feb 6, 2021·Pathogens·Gustavo Henrique Rodrigues Vale de MacedoLuís Cláudio Nascimento da Silva
May 21, 2021·Saudi Journal of Biological Sciences·Siju Kankalil GeorgeHarish Kumar Ks
Jul 27, 2021·Radiology Case Reports·Rahul BollamTung Phan

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