Abstract
Vancomycin-resistant enterococci (VRE) pose an emerging problem in hospitals worldwide. The present study was undertaken to determine the occurrence, species prevalence, antibacterial resistance, and phenotypic and genetic characteristics of VRE isolated in Riyadh hospitals, KSA. Two hundred and six isolates of enterococcal species were obtained from clinical samples. The antibiotic susceptibility of isolates and minimum inhibitory concentration (MIC) tests for vancomycin and teicoplanin were determined. Molecular typing of VRE isolates was carried out by using pulsed field gel electrophoresis (PFGE) and the resistance genotype was determined by polymerase chain reaction (PCR). VRE accounted for 3.9% of the isolates and were detected mostly in urine, wound and blood specimens isolated from ICU, internal medicine and surgical wards. All strains were identified to species level and were found to consist of E. faecalis (69.2%), E. faecium (11.3%), E. avium (2.1%), E. hirae (0.8%), E. casseliflavus (1.3%) and E. gallinarum (1.3%) species. According to the susceptibility data obtained, 8 (3.9%) out of 206 isolates were found to be VRE (MICs > 32 μg/ml). The vanA, vanB and vanC gene fragments of E. faecalis, E. faecium and E. gallina...Continue Reading
References
Sep 1, 1995·Journal of Clinical Microbiology·F C TenoverB Swaminathan
Jan 1, 1995·Journal of Clinical Microbiology·S Dutka-MalenP Courvalin
Jan 1, 1993·Journal of Bacteriology·M ArthurP Courvalin
Sep 1, 1997·Journal of Clinical Microbiology·S SatakeF C Tenover
Apr 16, 1999·Journal of Clinical Microbiology·M IevenH Goossens
Oct 26, 1999·Diagnostic Microbiology and Infectious Disease·J A KarlowskyD J Hoban
Dec 23, 1999·The Journal of Infectious Diseases·P DescheemaekerH Goossens
Jun 2, 2000·Journal of Clinical Microbiology·R R NelsonH Young
Jan 11, 2001·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M A SchoutenUNKNOWN European VRE Study Group
Apr 3, 2001·International Journal of Antimicrobial Agents·M G Zouain, G F Araj
Jan 25, 2003·Journal of Medical Microbiology·Edet E UdoTulsi D Chugh
Apr 4, 2003·The New England Journal of Medicine·Soju ChangUNKNOWN Vancomycin-Resistant Staphylococcus aureus Investigative Team
Apr 29, 2008·The Journal of Antimicrobial Chemotherapy·Mushtaq A KhanJohn P Hays
Sep 9, 2009·Indian Journal of Medical Microbiology·P M Giridhara UpadhyayaB L Umapathy
Aug 27, 2010·Journal of Clinical Microbiology·Susan M DonabedianPaul Bartlett
Citations
Jul 27, 2012·Epidemiology and Infection·M A KhanJ P Hays
Mar 26, 2014·International Journal of Environmental Research and Public Health·Wei JiaWen Wang
Dec 10, 2013·International Journal of Antimicrobial Agents·Souha S KanjMichael J Dowzicky
Nov 7, 2015·New Microbes and New Infections·N BourafaJ-M Rolain
Dec 17, 2015·Annals of Clinical Microbiology and Antimicrobials·Rayo Morfin-OteroMichael J Dowzicky
Aug 18, 2016·Journal of Global Antimicrobial Resistance·Nadjette BourafaJean-Marc Rolain
Jun 1, 2016·The Indian Journal of Medical Research·Chimanjita PhukanKandarpa K Saikia
Jun 2, 2016·Microbial Pathogenesis·Ali M SomilyAhmed A Al-Qahtani
Feb 1, 2017·Chinese Medical Journal·Fawzia E Alotaibi, Elham E Bukhari
Jun 29, 2016·Journal of Chemotherapy·Mohammad Z AbdelkareemSayed F Abdelwahab
Oct 17, 2018·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Mohammad Abdallah, Mohammad Al-Saafin
Apr 4, 2019·Interdisciplinary Perspectives on Infectious Diseases·Sridevi Shridhar, Biranthabail Dhanashree
Apr 10, 2019·Antimicrobial Resistance and Infection Control·Muhammad FarmanEsam I Azhar
Feb 6, 2021·Pathogens·Gustavo Henrique Rodrigues Vale de MacedoLuís Cláudio Nascimento da Silva
May 21, 2021·Saudi Journal of Biological Sciences·Siju Kankalil GeorgeHarish Kumar Ks
Jul 27, 2021·Radiology Case Reports·Rahul BollamTung Phan
Aug 6, 2021·Parasitology Research·Taehee ChangJong-Yil Chai