Prevalence and associated factors of knee osteoarthritis in a rural Chinese adult population: an epidemiological survey

BMC Public Health
Yuan LiuJun Hu

Abstract

The exact pathogenic mechanism of knee osteoarthritis (OA) is still unknown. With the exception of clinical treatment to alleviate symptoms, or total knee replacement, there is currently no effective treatment method. Consequently, an in-depth etiological and epidemiological study of knee OA can provide clues for diagnosis, treatment and scientific research, and will ultimately have a beneficial effect on public health. A cross-sectional community study in the rural village of Gaoyou was conducted in 3428 Chinese adults (aged ≥ 40 years). Subjects completed an interviewer-administered questionnaire, evaluating knee pain and associated disability, analgesia, use of health services, past medical history, walking, income, smoking, and use of oral contraceptives, and standardized weight-bearing knee radiographs were obtained. Patient demographic characteristics and biochemical parameters were recorded. Single-factor regression analysis indicated that age, overweight, central adiposity, high low-density lipoprotein cholesterol (LDLC), high total cholesterol (TC), high triglycerides (TG), dyslipidemia, hypertension and low income were the associated factors for knee OA in females; age, high LDLC, hypertension, low income and frequent...Continue Reading

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Citations

Apr 30, 2016·Technology and Health Care : Official Journal of the European Society for Engineering and Medicine·Pia C HermannRobert Pflugmacher
Jun 27, 2017·Rejuvenation Research·Nicola VeroneseStefania Maggi
Jul 17, 2018·Complementary Medicine Research·Yu-Ling WangYin Wang
Oct 3, 2019·Medicine·Qinguang XuXiang Wang
Sep 12, 2020·Physiotherapy Research International : the Journal for Researchers and Clinicians in Physical Therapy·Yolandi BrinkKaren Grimmer
Jan 10, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Bingbing ZhangYongsheng Sun
Nov 30, 2019·International Journal of Environmental Research and Public Health·Xueshan SunHengjin Dong
Jun 4, 2019·The Journal of Immunology : Official Journal of the American Association of Immunologists·Peng TengJun Hu
Jul 29, 2021·Nature Reviews. Rheumatology·Karen ChingChunyi Wen

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