Prevalence and Associations of Hypothyroidism in Indian Patients with Type 2 Diabetes Mellitus

Journal of Thyroid Research
Abilash NairT P Seena

Abstract

Both type 2 diabetes and hypothyroidism are highly prevalent disorders in the community. The existing data regarding prevalence of hypothyroidism in patients with diabetes comes mostly from small studies. There are only two studies with a sample size of more than 1000 diabetic patients, none of which have been done in South Asians. The present study evaluated patients with type 2 diabetes for presence of hypothyroidism and the clinical factors associated with it. The demographic, anthropometric, clinical, and biochemical parameters of consecutively enrolled patients with diabetes were systematically collected and analyzed. A total of 1152 middle aged patients with type 2 diabetes with a mean duration of diabetes of around 10 years were enrolled. Nearly 40 percent of the patients were obese and overweight, respectively, for South Asian standards and abdominal obesity was seen in around 90% patients. Clinical hypothyroidism (TSH>10 mIU/ml) was present in 113 of patients (9.83%) and another 68 patients (5.9%) had subclinical hypothyroidism (TSH 5-10 mIU/ml). Anemia (odds ratio : 2.19), overweight/obese status (odds ratio 2.07), and known dyslipidemia (odds ratio : 1.99) were found to have independent association with clinical hypo...Continue Reading

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Citations

Oct 5, 2019·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Sanjay KalraDeepak Khandelwal
Aug 23, 2019·Irish Journal of Medical Science·Roxana Maria TudorChristopher J Thompson
Aug 11, 2020·Journal of Basic and Clinical Physiology and Pharmacology·Md Anzar AlamShabnam Ansari
Nov 26, 2020·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Xiuting HuangLinong Ji
Aug 15, 2021·Drug Metabolism and Personalized Therapy·Md Anzar AlamNafis Haider
Aug 28, 2021·Drug Metabolism and Personalized Therapy·Md Anzar AlamNafis Haider

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Methods Mentioned

BETA
ESR

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SPSS Statistics
Excel

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