Prevalence and characteristics of mitral valve prolapse in military young adults in Taiwan of the CHIEF Heart Study.

Scientific Reports
Pang-Yen LiuGen-Min Lin


The prevalence of mitral valve prolapse (MVP) among middle- and older-aged individuals is estimated to be 2-4% in Western countries. However, few studies have been conducted among Asian individuals and young adults. This study included a sample of 2442 consecutive military adults aged 18-39 years in Hualien, Taiwan. MVP was defined as displacement of the anterior or posterior leaflet of the mitral valve to the mid portion of the annular hinge point > 2 mm in the parasternal long-axis view of echocardiography. Cardiac chamber size and wall thickness were measured based on the latest criteria of the American Society of Echocardiography. The clinical features of participants with MVP and those without MVP were compared using a two-sample t test, and the cardiac structures were compared using analysis of covariance with adjustment for body surface area (BSA). Eighty-two participants were diagnosed with MVP, and the prevalence was 3.36% in the overall population. Compared with those without MVP, participants with MVP had a lower body mass index (kg/m2) (24.89 ± 3.70 vs. 23.91 ± 3.45, p = 0.02) and higher prevalence of somatic symptoms related to exercise (11.0% vs. 4.9%, p = 0.02) and systolic click in auscultation (18.3% vs. 0.6%, ...Continue Reading


Oct 1, 1992·Australian and New Zealand Journal of Medicine·D E Wilcken
Mar 1, 1992·American Heart Journal·K HirataC F Wooley
Sep 1, 1989·Circulation·J K Perloff, J S Child
Apr 20, 1989·The New England Journal of Medicine·A R MarksA E Weyman
Feb 15, 1986·The American Journal of Cardiology·R B DevereuxN Reichek
Nov 1, 1986·The American Journal of Medicine·R B DevereuxP Kligfield
Nov 21, 1985·The New England Journal of Medicine·R A NishimuraA J Tajik
Dec 1, 1982·Annals of Internal Medicine·R B DevereuxI Sachs
Nov 1, 1981·The American Journal of Medicine·A D SantosW A Wallace
Feb 1, 1980·Annals of Internal Medicine·C V LeierC F Wooley
Jul 1, 1999·The New England Journal of Medicine·L A FreedEmelia J Benjamin
Dec 3, 2008·Annals of Internal Medicine·Jean-François AvierinosMaurice Enriquez-Sarano
Oct 23, 2009·The International Journal of Cardiovascular Imaging·Yasin TurkerHabil Yucel
Oct 21, 2015·Nature Reviews. Cardiology·Robert A LevineLeducq Mitral Transatlantic Network
Mar 24, 2016·Circulation·Francesca N DellingRamachandran S Vasan
Mar 23, 2018·International Journal of Environmental Research and Public Health·Kai-Wen ChenGen-Min Lin
Sep 23, 2018·Heart·Chrishan J NalliahPrashanthan Sanders
Dec 1, 2018·Endocrine, Metabolic & Immune Disorders Drug Targets·Jia-Wei LinGen-Min Lin
Mar 24, 2020·Progress in Cardiovascular Diseases·Konstantinos Dean BoudoulasHarisios Boudoulas

Related Concepts

Cell Wall
Mitral Valve Prolapse Syndrome

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Generating Insulin-Secreting Cells

Reprogramming cells or using induced pluripotent stem cells to generate insulin-secreting cells has significant therapeutic implications for diabetics. Here is the latest research on generation of insulin-secreting cells.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Epigenome Editing

Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.

Related Papers

The Canadian Journal of Cardiology
Michael ThealEva Lonn
Polskie Archiwum Medycyny Wewnętrznej
Ewa Kucharczyk-PetrykaMirosław Dłuzniewski
Archives of Internal Medicine
S M RetchinR A Waugh
Progress in Cardiovascular Diseases
Purvi ParwaniFrancesca N Delling
© 2021 Meta ULC. All rights reserved