Prevalence and characterization of integrons in blood culture Enterobacteriaceae and gastrointestinal Escherichia coli in Norway and reporting of a novel class 1 integron-located lincosamide resistance gene

Annals of Clinical Microbiology and Antimicrobials
Even HeirGeorg Kapperud

Abstract

Class 1 integrons contain genetic elements for site-specific recombination, capture and mobilization of resistance genes. Studies investigating the prevalence, distribution and types of integron located resistance genes are important for surveillance of antimicrobial resistance and to understand resistance development at the molecular level. We determined the prevalence and genetic content of class 1 integrons in Enterobacteriaceae (strain collection 1, n = 192) and E. coli (strain collection 2, n = 53) from bloodstream infections in patients from six Norwegian hospitals by molecular techniques. Class 1 integrons were also characterized in 54 randomly selected multiresistant E. coli isolates from gastrointestinal human infections (strain collection 3). Class 1 integrons were present in 10.9% of the Enterobacteriaceae blood culture isolates of collection 1, all but one (S. Typhi) being E. coli. Data indicated variations in class 1 integron prevalence between hospitals. Class 1 integrons were present in 37% and 34% of the resistant blood culture isolates (collection 1 and 2, respectively) and in 42% of the resistant gastrointestinal E. coli. We detected a total of 10 distinct integron cassette PCR amplicons that varied in size be...Continue Reading

References

Dec 10, 1987·Nucleic Acids Research·M Ouellette, P H Roy
Jan 1, 1995·Antimicrobial Agents and Chemotherapy·C M Collis, R M Hall
Jan 1, 1995·Antimicrobial Agents and Chemotherapy·C LévesqueP H Roy
Dec 1, 1995·Microbiology·G D Recchia, R M Hall
Feb 5, 2000·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·T M LeegaardE A Høiby
May 19, 2000·Antimicrobial Agents and Chemotherapy·D MazelJ Davies
Jul 18, 2000·Antimicrobial Agents and Chemotherapy·B GuerraM C Mendoza
Feb 13, 2001·FEMS Microbiology Letters·B S NieldH W Stokes
Aug 15, 2001·Antimicrobial Agents and Chemotherapy·P A WhiteW D Rawlinson
Aug 23, 2001·International Journal of Antimicrobial Agents·T M LeegaardE A Høiby
Feb 22, 2002·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Franz-Josef SchmitzMark E. Jones
May 11, 2002·Journal of Bacteriology·Christina M CollisRuth M Hall

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Citations

Jan 11, 2005·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Arnfinn SundsfjordKristin H Dahl
May 19, 2006·Emerging Infectious Diseases·Aarati N RaoJohn E McGowan
Apr 23, 2015·Microbiology·Sara DominguesKaare Magne Nielsen
May 7, 2009·FEMS Microbiology Reviews·Sally R PartridgeJonathan R Iredell
Jul 3, 2013·The Journal of Antimicrobial Chemotherapy·François GraveyVincent Cattoir
May 24, 2005·FEMS Immunology and Medical Microbiology·Erica L FonsecaAna C P Vicente
Oct 22, 2005·International Journal of Medical Microbiology : IJMM·Heike von Baum, Reinhard Marre
May 26, 2007·The Kaohsiung Journal of Medical Sciences·Lin-Li ChangChung-Yu Chang
Jul 22, 2019·Journal of Burn Care & Research : Official Publication of the American Burn Association·Siamak HeidarzadehAzad Khaledi
Sep 29, 2006·Antimicrobial Agents and Chemotherapy·Renee S LevingsSteven P Djordjevic
Jun 28, 2005·Antimicrobial Agents and Chemotherapy·Adeline AchardRoland Leclercq
Nov 3, 2016·Cold Spring Harbor Perspectives in Medicine·Stefan SchwarzBirte Vester
Jan 1, 2017·The Journal of Antimicrobial Chemotherapy·Xiao-Qing ZhuJian-Zhong Shen
Mar 8, 2007·Journal of Food Protection·Souwalak PhongpaichitUsa Chethanond
Dec 19, 2007·Antimicrobial Agents and Chemotherapy·Efthymia PetinakiRoland Leclercq
Oct 4, 2017·Nucleic Acids Research·Donna MatzovAda Yonath

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Datasets Mentioned

BETA
AJ561197
AAD26631

Methods Mentioned

BETA
PCR
electrophoresis

Software Mentioned

BLAST
Lasergene
RPS

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