Prevalence and clinical features of non-motor symptoms of essential tremor in Shanghai rural area

Parkinsonism & Related Disorders
Yiwen WuShengdi Chen

Abstract

Few studies regarding the epidemiology of essential tremor (ET) and its non-motor symptoms (NMS) have been conducted to date. We thus conducted a door-to-door survey to investigate the ET and its NMS and their clinical manifestations in a rural area of Shanghai, China. We recruited 19,614 residents (≥ 50 years old), living in Malu town, Shanghai. Investigations were divided into two steps. In first step, trained physicians conducted door-to-door surveys and reported probable ET subjects to movement disorder specialists. In the second step, participants with suspected ET had their diagnosis confirmed by movement disorder specialists. We randomly selected 123 subjects from those adults who screened negative for neurological conditions as healthy controls for the study of NMS. The prevalence of ET in individuals (≥ 50 years old) was 0.306% (PR = 3.06 per 1000). The mini-mental state examination (MMSE) scores were lower in ET patients than in controls (25.81 ± 4.20 vs. 26.63 ± 3.14, P= 0.024). Complaints of restless legs reported by ET patients were significantly higher than those in controls (P < 0.05). In contrast, we did not observe a significant difference for other NMS between ET patients and controls, including olfactory func...Continue Reading

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Citations

Apr 21, 2019·Neurology·Hortensia Alonso-NavarroFélix Javier Jiménez-Jiménez
May 23, 2019·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Rong LuoLing Chen
Mar 13, 2020·Sleep·Félix Javier Jiménez-JiménezJosé A G Agúndez
Jun 29, 2018·Frontiers in Neurology·Carmen Rodríguez-BlázquezPablo Martinez-Martin
Aug 11, 2020·Tremor and Other Hyperkinetic Movements·Yildizhan Sengul
Mar 24, 2021·Current Neurology and Neuroscience Reports·Félix Javier Jiménez-JiménezJosé A G Agúndez

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