Prevalence and Clinical Impact of IgE-Mediated Food Allergy in School Children With Asthma: A Double-Blind Placebo-Controlled Food Challenge Study

Allergy, Asthma & Immunology Research
Aneta KrogulskaKrystyna Wasowska-Królikowska

Abstract

Recent studies indirectly suggest a possible link between food allergy (FA) and asthma. Most of them have evaluated the occurrence of FA in asthmatic children, especially in the first year of life, using questionnaire-based studies or specific IgE (sIgE) assay. The aim of this study was to evaluate the prevalence and clinical impact of IgE-mediated FA in school children with asthma using a double-blind placebo-controlled food challenge (DBPCFC). The study group consisted of school children with atopic asthma who were admitted to the Department of Pediatric Allergology, Gastroenterology and Nutrition, Medical University of Lodz, for the evaluation of food hypersensitivity. The diagnosis of FA was established using questionnaires, sIgE analysis, and the DBPCFC. Asthma severity and asthma control state were also assessed. A relationship between consumed food and complaints was reported in 180 children (49.7%). Seventy children (19.3%) were sensitized to food allergens. IgE-mediated FA was confirmed in 24 children (6.6%), while 11 children (3%) demonstrated respiratory symptoms. Food-induced asthma exacerbations were observed in 9 patients (2.5%). Statistically significant differences in the prevalence of atopic dermatitis (P<0.002...Continue Reading

References

May 1, 1988·The Journal of Allergy and Clinical Immunology·E NovembreA Vierucci
Jan 1, 1994·American Journal of Respiratory and Critical Care Medicine·J M JamesH A Sampson
Aug 1, 1996·Australian and New Zealand Journal of Medicine·R K WoodsE H Walters
Jan 29, 2000·Archives of Disease in Childhood·C CaffarelliD J Atherton
Apr 20, 2002·Current Opinion in Allergy and Clinical Immunology·C E Baena-Cagnani, A Teijeiro
Sep 11, 2002·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·F Rancé, G Dutau
Jul 9, 2003·The Journal of Allergy and Clinical Immunology·Graham RobertsGideon Lack
Jul 26, 2003·Paediatric Respiratory Reviews·Graham Roberts, Gideon Lack
Oct 14, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C C RoehrB Niggemann
May 4, 2005·The Journal of Allergy and Clinical Immunology·Julie WangHugh A Sampson
Nov 3, 2005·The European Respiratory Journal·R PellegrinoJ Wanger
Feb 20, 2007·The Journal of Allergy and Clinical Immunology·S Allan BockHugh A Sampson
Mar 14, 2007·The Journal of Allergy and Clinical Immunology·Andrew H LiuRanjani Manjunath
May 1, 2007·Pediatric Pulmonology·Alyson B SimpsonEjaz Yousef
May 26, 2007·Paediatric Drugs·Janet L BeausoleilJonathan M Spergel
Jul 14, 2007·The Journal of Allergy and Clinical Immunology·Roberto J RonaCharlotte Madsen
Aug 8, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Graham Roberts
Feb 9, 2008·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Avigael H BenhamouPhilippe A Eigenmann
Apr 2, 2008·The Journal of Allergy and Clinical Immunology·Laurian ZuidmeerThomas Keil
Dec 17, 2008·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Nicola M VogelDavid M Lang
Feb 4, 2009·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A SchroederX Wang
Jun 16, 2009·The Journal of Allergy and Clinical Immunology·Anna Nowak-WegrzynUNKNOWN Adverse Reactions to Food Committee of American Academy of Allergy, Asthma & Immunology
Feb 16, 2010·The Journal of Pediatrics·Alyson B SimpsonJobayer Hossain
Apr 24, 2010·International Archives of Allergy and Immunology·Javier Cuesta-HerranzAna I Tabar
Jun 10, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A Gillman, Jo A Douglass
Jan 1, 2010·Journal of Asthma and Allergy·Anupama Kewalramani, Mary E Bollinger
Apr 5, 2011·Allergy, Asthma & Immunology Research·Tao ZhengZhou Zhu
Sep 24, 2013·The Journal of Allergy and Clinical Immunology. in Practice·James L FriedlanderWanda Phipatanakul
Nov 2, 2013·Allergy, Asthma & Immunology Research·Santiago Quirce, Araceli Diaz-Perales
Mar 4, 2014·Allergy, Asthma & Immunology Research·Miran ParkYoungshin Han
Nov 7, 2014·Allergy, Asthma & Immunology Research·Martín Bedolla-BarajasJaime Morales-Romero
Jan 2, 2015·Allergy, Asthma & Immunology Research·So Young ParkYou Sook Cho
Mar 3, 2015·Allergy, Asthma & Immunology Research·Bok Yang Pyun

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Citations

Jan 6, 2016·Pediatric Pulmonology·Aneta KrogulskaKrystyna Wąsowska-Królikowska
May 13, 2017·Allergy, Asthma & Immunology Research·Yuki OkadaAkira Akasawa
Oct 25, 2016·Allergy·S R Del GiaccoL Bjermer
Oct 17, 2017·Allergologia et immunopathologia·T A GonzagaG R S Segundo

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