Prevalence and correlation of infectious agents in hospitalized children with acute respiratory tract infections in Central China

PloS One
Jia LiuYingle Liu

Abstract

Acute respiratory tract infections (ARTIs) are associated with significant morbidity and mortality worldwide, especially in children under the age of 5 years. Almost 2 million children die from ARTIs each year, and most of them are from developing countries. The prevalence and correlation of pathogens in ARTIs are poorly understood, but are critical for improving case prevention, treatment, and management. In this study, we investigated the prevalence and correlation of infectious agents in children with ARTIs. A total of 39,756 children with one or more symptoms, including fever, cough, sore throat, tonsillitis, pharyngitis, herpangina, pneumonia, and bronchiolitis, were enrolled in the study. All patients were hospitalized in Wuhan Children's Hospital between October 1, 2010 and September 30, 2012, and were evaluated for infectious agents. Pathogens, including Mycoplasma pneumoniae, influenza A virus, influenza B virus, adenoviruses, respiratory syncytial virus, parainfluenza virus, Legionella pneumophila, Chlamydophila pneumoniae, and Coxiella burnetii, were screened simultaneously in patient blood samples using anti-pathogen IgM tests. Regression analysis was used to reveal correlations among the pathogens. Our results show...Continue Reading

References

Aug 1, 1988·American Journal of Diseases of Children·D A TristramL B Weiner
Mar 15, 2000·Scandinavian Journal of Infectious Diseases·J H TjhieC M Vandenbroucke-Grauls
Jul 18, 2000·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J A WeiglH J Schmitt
Oct 12, 2000·The Journal of Infection·M R KimG M Lee
Feb 8, 2002·The New England Journal of Medicine·Kenneth McIntosh
Mar 15, 2002·The Lancet Infectious Diseases·Brian G WilliamsChristopher Dye
Mar 13, 2003·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·W RastawickiR Gierczyski
Nov 11, 2003·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·C Wyder-WesthC Aebi
Feb 5, 2004·European Journal of Epidemiology·Waldemar RastawickiRafał Gierczyński
Apr 10, 2004·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Tzou-Yien LinKou-Chien Tsao
Jun 18, 2004·Emerging Infectious Diseases·James A MullinsLarry J Anderson
Feb 13, 2008·The Journal of Infectious Diseases·Daniel E RothSunita Vohra
May 6, 2008·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Cristina CalvoInmaculada Casas
Sep 13, 2008·Acta Paediatrica·Hilary E StempelDanielle M Zerr
Oct 3, 2008·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Gláucia Paranhos-BaccalàDaniel Floret
Feb 7, 2009·The New England Journal of Medicine·Caroline Breese HallPeter Szilagyi
Feb 25, 2009·Journal of Medical Virology·Massimiliano FabbianiMaria Grazia Cusi
Feb 4, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J S CasalegnoB Lina
May 27, 2010·JAMA : the Journal of the American Medical Association·James A BerkleyD James Nokes
Feb 12, 2011·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·V J ChalkerT G Harrison
Jul 20, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Y JinZ-J Duan
Jan 31, 2012·The Journal of Antimicrobial Chemotherapy·Gabriela WarburgJacob Strahilevitz
Feb 11, 2012·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·A PolkowskaO Lyytikäinen
Dec 17, 2014·Medicine·Marcela González-Del VecchioEmilio Bouza

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Citations

May 6, 2016·Frontiers in Microbiology·Gretchen L ParrottJiro Fujita
Aug 15, 2015·Clinical and Experimental Vaccine Research·Hyeon-Jong Yang
Feb 28, 2017·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Mingyu XieBaimao Zhong
Feb 6, 2017·Infectious Disease Clinics of North America·Eleni E Magira, Sryros Zakynthinos
Jul 24, 2015·Journal of Clinical Microbiology·Rebecca J BrownVictoria J Chalker
Jan 31, 2020·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Matheus Silva AlvesLidio Gonçalves Lima-Neto

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Statistical Product and Service Solutions ( SPSS )
Statistics Analysis System ( SAS )

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