Prevalence and Determinants of Chronic Kidney Disease Among Hypertensive Cameroonians According to Three Common Estimators of the Glomerular Filtration Rate.

The Journal of Clinical Hypertension
Francois Folefack KazeKathleen Blackett Ngu

Abstract

Hypertension is a risk factor for renal diseases, which, in turn, are precursors of hypertension. The authors assessed the prevalence and determinants of chronic kidney disease (CKD) among 336 hypertensive adult Cameroonians (mean age, 60.9±11.3 years; 63.4% women) at Yaoundé. Any participant with an estimated glomerular filtration rate <60 mL/min/1.73 m(2) regardless of the equation used (Cockcroft-Gault [CG], Modification of Diet in Renal Disease [MDRD], and Chronic Kidney Disease Epidemiology Collaboration [CKD-EPI]) and/or dipstick proteinuria was reviewed 3 months later. Participants presented a high prevalence of diabetes (18.5%), dyslipidemia (17.6%), gout/hyperuricemia (10.7%), overweight/obesity (68.8%), self-medication (37.5%), and alcohol consumption (33.3%). Hypertension was uncontrolled in 265 patients (78.9%). The prevalence of CKD was 49.7%, 50.0%, and 52.1% according to MDRD, CKD-EPI, and CG equations, respectively. Advanced age, adiposity, and severity of hypertension were determinants of CKD. Nearly half of the hypertensive patients had CKD regardless of the estimators used, predicted by well-known risk factors.

References

Jan 1, 1976·Nephron·D W Cockcroft, M H Gault
Dec 1, 1996·Journal of Clinical Epidemiology·P PeduzziA R Feinstein
May 29, 1998·International Journal of Epidemiology·J C MbanyaB Balkau
Jul 17, 2003·Kidney International. Supplement·Saraladevi Naicker
Oct 1, 2003·Blood Pressure Monitoring·Eoin O'Brien
Oct 22, 2003·Journal of the American Society of Nephrology : JASN·Chi-Yuan HsuMichael G Shlipak
Jan 18, 2005·Lancet·Patricia M KearneyJiang He
Jul 15, 2005·Kidney International. Supplement·Dante AmatoRamon Paniagua
Aug 16, 2006·Annals of Internal Medicine·Andrew S LeveyUNKNOWN Chronic Kidney Disease Epidemiology Collaboration
Mar 3, 2007·Clinical Chemistry·Andrew S LeveyUNKNOWN Chronic Kidney Disease Epidemiology Collaboration
Mar 28, 2008·Current Hypertension Reports·Yousri M Barri
Aug 22, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ernest K SumailiNazaire M Nseka
May 6, 2009·Annals of Internal Medicine·Andrew S LeveyUNKNOWN CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
Jan 27, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·John B EastwoodFrancesco P Cappuccio
May 3, 2011·Renal Failure·Charlotte OsafoDwomoa Adu
Jan 1, 2013·Kidney International Supplements

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Citations

Dec 7, 2019·Clinical Kidney Journal·June FabianSaraladevi Naicker
May 13, 2020·Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia·Samuel Ayokunle DadaBolade Dele-Ojo
Sep 25, 2020·BMC Nephrology·Jerry Brown AsenehValirie Ndip Agbor
Mar 3, 2021·Clinical and Experimental Nephrology·Francois Folefack KazeAndre-Pascal Kengne
Aug 6, 2021·BMJ Global Health·Cindy GeorgeUNKNOWN CKD-Africa Collaboration

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