Prevalence and Determinants of Glycemic Abnormalities in Cardiac Surgery Patients without a History of Diabetes: A Prospective Study

Frontiers in Endocrinology
Roma Y GianchandaniRodica Pop-Busui

Abstract

To evaluate the prevalence and persistence of postoperative glycemic abnormalities in patients without a history of diabetes, undergoing cardiac surgery (CS). Ninety-two patients without diabetes with planned elective CS procedures at a tertiary institution were evaluated preoperatively and 3 months postoperatively for measures of glucose control including hemoglobin A1c, fasting plasma glucose, 2-h post oral glucose load, and insulin levels. Data from the hospital course were recorded. Valid data were available from 61 participants at 3 months; 59% had prediabetes and 10% had diabetes preoperatively by one or more diagnostic criteria and continued to be dysglycemic at 3 months. Preoperative A1C was an independent predictor of postoperative hyperglycemia (p = 0.02). Insulin resistance and BMI rather than glycemic abnormalities before surgery were associated with a longer duration of the postoperative insulin infusion (p = 0.004, p = 0.048). Seventy percent of CS patients without known diabetes met criteria for diabetes or prediabetes preoperatively, and these abnormalities persisted after surgery.

References

Sep 21, 2006·European Heart Journal·Da-Yi HuUNKNOWN China Heart Survey Group
Jul 9, 2008·Scandinavian Cardiovascular Journal : SCJ·Thomas AlseriusTorbjörn Ivert
Aug 14, 2008·The Journal of Clinical Endocrinology and Metabolism·Deborah J WexlerEnrico Cagliero
May 26, 2009·Lancet·Kathleen M DunganJean-Charles Preiser
Jul 16, 2010·The Journal of Clinical Endocrinology and Metabolism·Hiroaki SatoThomas Schricker
Aug 23, 2011·Diabetes Technology & Therapeutics·Roma Y GianchandaniRodica Pop-Busui
May 23, 2012·Hospital Practice·Roma Y GianchandaniRodica Pop-Busui
Dec 30, 2014·Diabetes Care·UNKNOWN American Diabetes Association

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BETA
coronary artery bypass

Software Mentioned

PASW

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