Prevalence and epidemiological associates of novel psychedelic use in the United States adult population

Journal of Psychopharmacology
James D SextonPeter S Hendricks

Abstract

Novel psychedelics approximate classic psychedelics, but unlike classic psychedelics, novel psychedelics have been used by humans for a shorter period of time, with fewer data available on these substances. The purpose of this study was to determine the prevalence of novel psychedelic use and the associations of novel psychedelic use with mental health outcomes. We estimated the prevalence of self-reported, write-in lifetime novel psychedelic use and evaluated the associations of novel psychedelic use with psychosocial characteristics, past month psychological distress, and past year suicidality among adult respondents pooled from years 2008-2016 of the National Survey on Drug Use and Health (weighted n=234,914,788). A fraction (weighted n=273,720; 0.12%) reported lifetime novel psychedelic use. This cohort tended to be younger, male, and White, have greater educational attainment but less income, be more likely to have never been married, engage in self-reported risky behavior, and report lifetime illicit use of other drugs, particularly classic psychedelics (96.9%). (2-(4-Bromo-2,5-dimethoxyphenyl)ethanamine) (2C-B) (30.01%), (2,5-dimethoxy-4-iodophenethylamine) (2C-I) (23.9%), and (1-(2,5-dimethoxy-4-ethylphenyl)-2-aminoetha...Continue Reading

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Citations

Apr 8, 2020·Frontiers in Pharmacology·Esther PapaseitMagí Farré
Mar 16, 2021·Journal of Psychopharmacology·Otto SimonssonPeter S Hendricks
Apr 17, 2021·ACS Pharmacology & Translational Science·Richard J ZeifmanCory R Weissman
Jul 15, 2021·Scientific Reports·Otto SimonssonPeter S Hendricks
Aug 7, 2021·Toxics·José Manuel MateyMaría A Martínez

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