Prevalence and European comparison of dementia in a ≥75-year-old composite population in Spain

Acta Neurologica Scandinavica
Javier Virués-OrtegaSpanish Epidemiological Studies on Ageing Group

Abstract

To estimate dementia prevalence in Spain. Nine probabilistic and geographically defined samples participated. A screening design based on the MMSE was implemented. Positively screened individuals underwent clinical evaluation. The total number of cases in Spain was estimated. Prevalence was confronted to that of other European countries. Five hundred and forty-six persons aged ≥75 participated, 49 had dementia (35 with Alzheimer's disease [AD], 10 with vascular dementia [VD], 4 other; 25 first diagnosed in the study). Age- and sex-adjusted prevalence and estimated nationwide cases were 7.5% (95% CI 5.4-9.7), 5.6 (95% CI 3.7-7.5) and 1.4 (95% CI 0.5-2.3), and 290,000 (95% CI 208,000-372,000), 214,000 (95% CI 141,000-288,000) and 54,000 (95% CI 20,000-88,000) for dementia, AD and VD, respectively. Dementia prevalence in Spain is comparable to other European populations, while a high number of undiagnosed cases live in the community. The potential impact of Mediterranean diet, hypertension control and decreasing vascular risk factors is discussed.

References

Dec 1, 1994·Aging : Clinical and Experimental Research·S MaggiL Amaducci
Oct 1, 1993·International Journal of Epidemiology·P A SaundersA Scott
May 12, 1993·JAMA : the Journal of the American Medical Association·R M CrumM F Folstein
Jul 27, 1999·Haemostasis·M M BretelerA Hofman
Mar 29, 2002·Movement Disorders : Official Journal of the Movement Disorder Society·Luis Erik ClaveríaJesús de Pedro-Cuesta
May 15, 2003·JAMA : the Journal of the American Medical Association·Katharina Wolf-MaierFenicia Vescio
May 20, 2003·Journal of Neurology, Neurosurgery, and Psychiatry·T RahkonenR Sulkava
Oct 17, 2009·Acta Neurologica Scandinavica·D GavrilaC Navarro
Oct 17, 2009·Current Opinion in Clinical Nutrition and Metabolic Care·Catherine FéartPascale Barberger-Gateau

❮ Previous
Next ❯

Citations

May 28, 2013·Archives of Gerontology and Geriatrics·Beatriz León-SalasPablo Martínez-Martín
Feb 1, 2013·Dementia and Geriatric Cognitive Disorders·Pricila Cristina Correa RibeiroRoberto Alves Lourenço
Nov 19, 2011·BMC Neurology·Emiliano Rodríguez-SánchezManuel A Gómez-Marcos
Oct 23, 2013·PloS One·Miguel Angel Tola-ArribasBárbara Díaz-Gómez
Jun 1, 2015·Atencion primaria·María del Canto de Hoyos-AlonsoÁngel Otero Puime
Dec 3, 2014·Neurología : publicación oficial de la Sociedad Española de Neurología·M C de Hoyos-AlonsoA Otero
Mar 2, 2013·International Journal of Geriatric Psychiatry·Blazej MisiakAndrzej Kiejna
Jan 9, 2014·Geriatrics & Gerontology International·Abel E González-VélezUNKNOWN Spanish Research Group on Quality of Life and Ageing
Mar 13, 2018·Alzheimer Disease and Associated Disorders·Mary H KosmidisNikolaos Scarmeas
Nov 28, 2012·European Journal of Clinical Pharmacology·Pilar Avila-CastellsUNKNOWN Registry Dementia of Girona Study Group
Oct 8, 2015·Journal of Alzheimer's Disease : JAD·Sergio SalmerónPedro Abizanda
Sep 3, 2019·Nutrición hospitalaria·Lucía Arias-FernándezAlberto Lana Pérez
May 20, 2020·Alzheimer's Research & Therapy·Anna PonjoanRafel Ramos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.