Abstract
Limited amount of data suggest that patients with aortic stenosis and pulmonary hypertension (PH) who undergo transcatheter aortic valve replacement (TAVR) experience decrease in PH postprocedure. Inconsistent use of systolic pulmonary artery pressure cut-off values in previous studies limits our ability to draw meaningful conclusions regarding the prognostic role of PH in assessment of TAVR candidates. A total of 415 consecutive patients who underwent TAVR were included in the present study. Two groups were compared based on receiver-operating characteristics curve analysis for the best SPAP value to predict outcome, yielding 2 study groups of no/mild PH (≤50 mm Hg; n = 172, 41%) versus moderate/severe PH (>50 mm Hg; n = 243, 59%). Demographics and co-morbidities were comparable between the 2 groups; however, right-sided cardiac failure (35% vs 19.8%, p = 0.02) and mitral regurgitation (18.4% vs 8.6%, p = 0.007) were more frequent in patients with moderate/severe PH. Procedural characteristics and complications were comparable between the groups. Although there was an early overall decrease in SPAP postprocedure, only 26% of moderate/severe patients with PH experienced a significant decrease in SPAP (>10 mm Hg). The 30-day (14...Continue Reading
References
Jun 26, 2007·The Annals of Thoracic Surgery·Ramdas G PaiRamesh C Bansal
Jan 26, 2010·Journal of the American College of Cardiology·Josep Rodés-CabauEric Horlick
Jul 14, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Lawrence G RudskiNelson B Schiller
Feb 3, 2011·Current Cardiology Reviews·André DenaultLouis Perrault
Feb 8, 2011·The American Journal of Cardiology·Itsik Ben-DorRon Waksman
Feb 16, 2011·The Journal of Thoracic and Cardiovascular Surgery·Akin CamSamir R Kapadia
Mar 2, 2011·Heart·Surinder JandaJohn Swiston
May 21, 2011·The Journal of Thoracic and Cardiovascular Surgery·Spencer J MelbyRalph J Damiano
Oct 5, 2011·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Christine S ZuernAxel Bauer
Jul 24, 2012·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Itsik Ben-DorRon Waksman
Sep 11, 2012·The Journal of Thoracic and Cardiovascular Surgery·Eric E RoselliEugene H Blackstone
Oct 3, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Arie Pieter KappeteinUNKNOWN Valve Academic Research Consortium (VARC)-2
Jan 23, 2013·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Israel M BarbashRon Waksman
Oct 25, 2013·Circulation·Marco BarbantiUNKNOWN Placement of Aortic Transcatheter Valve Trial Investigators
Oct 31, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Jan-Malte SinningMariuca Vasa-Nicotera
Dec 18, 2013·The Journal of Thoracic and Cardiovascular Surgery·Dong Seop JeongPyo Won Park
Feb 28, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Manuel WilbringKonstantin Alexiou
Citations
Mar 22, 2016·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Ricardo O EscárcegaRon Waksman
Feb 10, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Yan-Biao LiaoMao Chen
Jan 29, 2016·European Heart Journal·Rishi PuriJosep Rodés-Cabau
Mar 16, 2016·The Lancet. Respiratory Medicine·Marius M HoeperJ Simon R Gibbs
Jul 11, 2016·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Edward KoifmanRon Waksman
Oct 30, 2016·The American Journal of Cardiology·Mengyao TangJian'an Wang
Oct 13, 2016·International Journal of Cardiology·V J NijenhuisM C Post
Jan 27, 2017·Cardiology and Therapy·Dagmar F Hernandez-Suarez, Angel López-Candales
Dec 31, 2016·Annals of the American Thoracic Society·Ryo YanagisawaKeiichi Fukuda
Dec 28, 2017·European Heart Journal·Javier BermejoUNKNOWN Sildenafil for Improving Outcomes after VAlvular Correction (SIOVAC) investigators
Oct 4, 2017·Heart·Ahmad MasriJoão L Cavalcante
Mar 22, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Robert SchuelerChristoph Hammerstingl
Jun 10, 2017·Pulmonary Circulation·Raj ParikhRajive Tandon
Jan 29, 2019·Journal of the American Heart Association·Krishna K PatelMilind Y Desai
Jun 6, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Stefanie KeymelVerena Veulemans
Jul 3, 2017·The International Journal of Cardiovascular Imaging·Pawel KleczynskiDariusz Dudek
Jul 2, 2017·Cardiology and Therapy·Anthony A BavryWade W Stinson
Jan 11, 2020·Acta Cardiologica·Mihai StrachinaruMarcel L Geleijnse
May 27, 2020·European Journal of Heart Failure·Evelyn Santiago-VacasAntoni Bayes-Genis
Nov 7, 2017·European Heart Journal Cardiovascular Imaging·Franck LevyChristophe Tribouilloy
Jun 8, 2018·Frontiers in Cardiovascular Medicine·Micha T MaederHans Rickli
Mar 20, 2020·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·M S van MourikM M Vis
Jan 6, 2021·Journal of the American Heart Association·Javier BermejoUNKNOWN SIOVAC (“Sildenafil for Improving Outcomes after VAlvular Correction”) Investigators
Apr 23, 2020·The American Journal of Cardiology·Clément BèclePierre Lantelme