Prevalence and impact of severe fatigue in adolescent and young adult cancer patients in comparison with population-based controls

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
Hanneke PoortWinette T A van der Graaf

Abstract

The current study determined the prevalence of severe fatigue in adolescent and young adult (AYA) cancer patients (aged 18-35 years at diagnosis) consulting a multidisciplinary AYA team in comparison with gender- and age-matched population-based controls. In addition, impact of severe fatigue on quality of life and correlates of fatigue severity were examined. AYAs with cancer (n = 83) completed questionnaires including the Checklist Individual Strength (CIS-fatigue), Quality of Life (QoL)-Cancer Survivor, Hospital Anxiety and Depression Scale (reflecting psychological distress), and the Cancer Worry Scale (reflecting fear of cancer recurrence or progression). The vast majority of participants had been treated with chemotherapy (87%) and had no active treatment at the time of participation (73.5%). Prevalence of severe fatigue (CIS-fatigue score ≥35) in AYAs with cancer (48%, n = 40/83) was significantly higher in comparison with matched population-based controls (20%, n = 49/249; p < .001). Severely fatigued AYAs with cancer reported lower QoL compared to non-severely fatigued AYAs with cancer (p < .05). Female gender, being unemployed, higher disease stage (III-IV) at diagnosis, receiving active treatment at the time of study...Continue Reading

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Citations

Jan 31, 2019·Acta Oncologica·Synne-Kristin H BøhnKristin V Reinertsen
Jan 15, 2020·Journal of Adolescent and Young Adult Oncology·Yu KeAlexandre Chan
Sep 17, 2020·Journal of Adolescent and Young Adult Oncology·Carol A DeNysschenBridget Zimmerman
Feb 23, 2019·Journal of Adolescent and Young Adult Oncology·Erik NoweKristina Geue
Feb 7, 2020·Current Treatment Options in Oncology·Melissa S Y ThongVolker Arndt
Feb 6, 2021·Cancer Treatment and Research Communications·Camila M Telles
Jun 2, 2021·Pediatric Blood & Cancer·Maureen E LyonJichuan Wang
Sep 3, 2021·Journal of Cancer Survivorship : Research and Practice·Alexandra SmithLarissa Nekhlyudov

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