Prevalence and incidence of dyslipidaemia among adults in Africa: a systematic review and meta-analysis protocol

BMJ Open
Jean Jacques N NoubiapAndré Pascal Kengne

Abstract

Cardiovascular disease (CVD) is the leading cause of death globally and disproportionately affects low-income and middle-income countries. Dyslipidaemia is an important modifiable risk factor for CVD. There are important knowledge gaps regarding the population levels of lipid variables and frequency of non-optimal levels in populations within Africa. We propose to conduct a systematic review to determine the prevalence and occurrence of dyslipidaemia in adult populations within countries in Africa. We will perform a comprehensive search to identify all possible published and unpublished studies on the prevalence or incidence of dyslipidaemia in Africa reported from 1 January 1980, without language restriction. The scientific databases PubMed MEDLINE, EMBASE and ISI Web of Science will be searched, as well as Grey literature. Following study selection, full-text papers acquisition, and data extraction and synthesis, we will appraise the quality of studies and risk of bias, and assess heterogeneity. Prevalence/incidence data will be summarised by country and geographic regions and a meta-analysis will be conducted for variables defined identically across studies. Variance stabilising transformations will be applied as appropriate...Continue Reading

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Citations

Feb 9, 2016·Foodborne Pathogens and Disease·Miao GuoAbani K Pradhan
Jun 23, 2016·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Chengyi DingSiyan Zhan
May 24, 2020·International Journal of Environmental Research and Public Health·Timotheus B Darikwa, Samuel O Manda
Jul 9, 2021·Drug Metabolism and Personalized Therapy·Mohd Aleemuddin QuamriBarkat Farooqui Ali

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