Prevalence and Intensity of Pain and Other Physical and Psychological Symptoms in Adolescents and Young Adults Diagnosed with Cancer on Referral to a Palliative Care Service

Journal of Adolescent and Young Adult Oncology
Rachel E HughesKate Thompson

Abstract

While adolescent and young adult (AYA) oncology is recognized as a distinct specialty, there remains a paucity of literature documenting symptomatology in this cohort. This study aimed to identify the prevalence, severity, and mechanism of pain and other symptoms in AYA patients referred to a palliative care service in a specialist Australian cancer center. A retrospective design analyzed the case file data of 33 eligible AYA patients aged 15-25 years old at diagnosis and two randomly selected control groups of patients >25 years old: unmatched and matched for diagnosis and sex. All cases were referred to the palliative care service between July 2009 and June 2012. Descriptive statistics, analysis of Edmonton Symptom Assessment Scale (ESAS) and Edmonton Classification System of Cancer Pain (ECS-CP) data, and non-parametric tests were performed. The most common malignancies among the AYA patients were sarcoma and hematological cancers. All AYA patients reported pain syndrome on the ECS-CP compared with 85% of the matched controls (p=0.018). An age group effect was found for mechanisms of pain (p=0.035). A trend toward more neuropathic pain among AYA cases was also found (59% vs. 39%). The most common ESAS symptoms in AYAs were p...Continue Reading

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Citations

Oct 20, 2018·Journal of Adolescent and Young Adult Oncology·Kelly R PeckDoralina L Anghelescu
Jul 30, 2019·Pediatric Research·L Lee DupuisLillian Sung
Aug 8, 2020·Journal of Adolescent and Young Adult Oncology·Kevin MaddenEduardo Bruera
Oct 11, 2016·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Kimberson TancoEduardo Bruera
Jul 19, 2019·Journal of Pain and Symptom Management·Lauri A LinderCatherine Fiona Macpherson
Feb 6, 2021·Cancer Treatment and Research Communications·Camila M Telles

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