PMID: 11925989Apr 3, 2002Paper

Prevalence and intensity of Wuchereria bancrofti antigenaemia in Sri Lanka by Og4C3 ELISA using filter paper-absorbed whole blood

Transactions of the Royal Society of Tropical Medicine and Hygiene
Mirani V WeerasooriyaE Kimura

Abstract

In Sri Lanka 2741 people from Matara, an endemic area for Wuchereria bancrofti, were examined in 1996/97 for microfilariae by 60-microL blood smear and for circulating filarial antigens by Og4C3 ELISA using filter paper-absorbed whole blood. The overall prevalence of microfilaraemia was 3.4%, and that of antigenaemia 14.4%. The prevalence of antigen-positive and microfilaria-negative people was 11.3%. Analysed by age-group, antigenaemia prevalence was similar in all groups, and the average number of antigen units was already very high in the age-group < 10 years, indicating that the infection started in early childhood. Among those who were antigen positive, the microfilaria prevalence was lower in females than in males. Diethylcarbamazine treatment eliminated microfilariae in 78% of the positives. However, 17 months after the treatment, antigenaemia was still positive in 76% of those who were parasitologically cured.

References

Sep 1, 1994·The American Journal of Tropical Medicine and Hygiene·P J LammieM L Eberhard
Dec 1, 1995·Annals of Tropical Medicine and Parasitology·D W MeyrowitschW H Makunde
Jan 1, 1997·Transactions of the Royal Society of Tropical Medicine and Hygiene·J NorõesD Addiss
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May 1, 1999·Tropical Medicine & International Health : TM & IH·M ItohE Kimura

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Citations

Feb 1, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·L K DasL J Debritto
Jan 15, 2011·Journal of Tropical Medicine·Sumadhya Deepika FernandoSenaka Rajapakse
May 9, 2014·Political Analysis : an Annual Publication of the Methodology Section of the American Political Science Association·Brad Verhulst, Peter K Hatemi
Nov 8, 2008·Science·James H Fowler, Darren Schreiber

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