Prevalence and mortality of patients with multiple sclerosis in France in 2012: a study based on French health insurance data

Journal of Neurology
Stéphanie FoulonAlain Weill

Abstract

Data on the prevalence of multiple sclerosis (MS) in France are scarce. National and regional updated estimates are needed to better plan health policies. In this nationwide study, we provided estimates of the prevalence of MS in France in 2012 and mortality rate in 2013. MS cases were identified in the French national health insurance database (SNIIRAM-PMSI) using reimbursement data for disease-modifying treatment, long-term disease status for MS, disability pension for MS, and hospitalisation for MS (MS ICD-10 code: G35). We identified 99,123 MS cases, corresponding to an overall crude prevalence rate of 151.2 per 100,000 inhabitants [95% confidence interval (CI) 150.3-152.2]: 210.0 per 100,000 in women (95% CI 208.4-211.5) and 88.7 per 100,000 in men (95% CI 87.6-89.7). The overall prevalence rate was 155.6 per 100,000 inhabitants (95% CI 154.7-156.6) after standardization on the 2013-European population. We observed a prevalence gradient with a higher prevalence (190-200 per 100,000) in North-Eastern France and a lower prevalence in Southern and Western France (126-140). The crude mortality rate in 2013 was 13.7 per 1,000 MS cases (11.4 in women and 20.3 in men). The standardized mortality ratio was 2.56 (95% CI 2.41-2.72)....Continue Reading

References

Feb 15, 2007·Journal of Neurology, Neurosurgery, and Psychiatry·Sandra VukusicChristian Confavreux
Jan 29, 2010·Revue D'épidémiologie Et De Santé Publique·C Sagnes-RaffyM Clanet
Jun 17, 2010·Brain : a Journal of Neurology·Agnes FromontThibault Moreau
Apr 12, 2011·Journal of Neurology, Neurosurgery, and Psychiatry·Steve SimpsonBruce Taylor
Aug 26, 2011·Journal of Neurology, Neurosurgery, and Psychiatry·E KingwellH Tremlett
Feb 23, 2012·Multiple Sclerosis : Clinical and Laboratory Research·Haritina El AdssiUNKNOWN LORSEP Group
May 2, 2012·Multiple Sclerosis : Clinical and Laboratory Research·S Otero-RomeroE Bufill
Jan 3, 2013·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·A GajofattoM D Benedetti
Jul 10, 2013·Neurology·Antonio ScalfariGeorge C Ebers
Sep 21, 2013·Journal of Neurology, Neurosurgery, and Psychiatry·I S MackenzieJ O'Riordan
Sep 28, 2013·BMC Neurology·Elaine KingwellRuth Ann Marrie
Nov 13, 2014·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·P BlinN Moore
Dec 31, 2014·La Revue de médecine interne·G MoulisL Sailler
Apr 17, 2015·Multiple Sclerosis and Related Disorders·D W KaufmanG Cutter
Jan 18, 2017·Advances in Experimental Medicine and Biology·Daiana Bezzini, Mario A Battaglia

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Citations

May 3, 2018·Statistical Methods in Medical Research·Jonathan RouxEmmanuelle Leray
Oct 16, 2018·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S CondéUNKNOWN Réseau NeuroSEP Auvergne
Apr 11, 2019·International Journal of Preventive Medicine·Vahid AhmadipanahmehrabadiBehzad Mahaki
Sep 8, 2019·European Journal of Epidemiology·Chantelle MurleyFei Yang
Nov 14, 2019·Journal of Aging and Health·Ivan R Molton, Anne Ordway
Jul 16, 2020·Orphanet Journal of Rare Diseases·Christina BergqvistPierre Wolkenstein
Feb 12, 2020·PharmacoEconomics Open·Olivier HeinzlefJuliette Longin
Sep 22, 2017·Multiple Sclerosis Journal - Experimental, Translational and Clinical·Delphine LefeuvreAlain Weill
Sep 15, 2020·Multiple Sclerosis Journal - Experimental, Translational and Clinical·Alice GuilleuxEmmanuelle Leray
Nov 3, 2020·Frontiers in Neurology·Christos BakirtzisNikolaos Grigoriadis
Jun 12, 2021·Frontiers in Immunology·Priyanka Devi-MarulkarFrédérique Michel
Jun 25, 2021·Expert Review of Pharmacoeconomics & Outcomes Research·Olivier VandhuickArnaud Kwiatkowski
Aug 20, 2021·Multiple Sclerosis : Clinical and Laboratory Research·Hélène TillautEmmanuelle Leray
Nov 26, 2021·Acta Neurologica Scandinavica·Natasha SmyrkeDeborah Mason
Sep 29, 2020·Neurology. Clinical Practice·Astrid Barataud-ReilhacEmmanuelle Leray

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