PMID: 11337187May 5, 2001Paper

Prevalence and phenotypes of erythromycin-resistant Streptococcus pneumoniae in Shanghai, China

Diagnostic Microbiology and Infectious Disease
M WangF Wang

Abstract

Bacterial resistance of Streptococcus pneumoniae against erythromycin and clindamycin and resistance phenotypes of erythromycin-resistant Streptococcus pneumoniae were investigated. The MICs of erythromycin and clindamycin against 345 strains of Streptococcus pneumoniae were tested with agar dilution method; the phenotypes of erythromycin-resistant Streptococcus pneumoniae were detected by double-disk test. One hundred and eighty-three and 171 of 345 (53.0% and 49.6%) of isolates had MICs > or =1 microg/ml for erythromycin and for clindamycin. Among erythromycin-resistant Streptococcus pneumoniae, the percentage of cMLS, iMLS and M phenotype was 90.3% (159/176), 5.7% (10/176) and 4.0% (7/176), respectively. The incidence of erythromycin-resistant Streptococcus pneumoniae is very high in Shanghai. The main phenotype is cMLS.

References

Dec 1, 1993·The Journal of Antimicrobial Chemotherapy·H SeppäläP Huovinen
Aug 1, 1996·Diagnostic Microbiology and Infectious Disease·R N JonesA Wanger
Jun 11, 1998·Emerging Infectious Diseases·C A Widdowson, K P Klugman

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Citations

Jan 18, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Roland Leclercq
Sep 25, 2012·International Journal of Antimicrobial Agents·Saber Yezli, Han Li
Feb 19, 2013·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Ivan Fan-Ngai HungRicardo Zotomayor
Jan 14, 2017·Frontiers in Microbiology·Yanming LiChen Wang

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