Prevalence and Predictors of Insulin Resistance in Non-Obese Healthy Young Females in Qatar

International Journal of Environmental Research and Public Health
Mohamed A ElrayessAbdelhamid Kerkadi

Abstract

The state of Qatar suffers from diabetes epidemic due to obesity-associated metabolic syndrome. However, the prevalence of insulin resistance prior to obesity, which could play an important role in the high prevalence of diabetes, has not yet been described. This study aims to compare the prevalence of insulin resistance in apparently healthy non-obese and obese participants from Qatar and identify the predictors of insulin resistance in different body mass index (BMI)-groups. In this cross-sectional study, 150 young healthy females from Qatar were dichotomized into four groups (underweight, normal weight, overweight and obese) based on their BMI. Anthropometric measures as well as fasting plasma levels of lipids, adipokines, blood glucose and insulin were recorded. The prevalence of insulin resistance as per homeostatic model assessment of insulin resistance (HOMA-IR) was estimated and differences between insulin sensitive and insulin resistant were compared. Linear models were used to identify predictors of insulin resistance in every BMI group. Prevalence of insulin resistance in non-obese healthy females from Qatar ranges between 7% and 37% and increases with BMI. Overall, predictors of insulin resistance in the Qatari popu...Continue Reading

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Citations

Oct 15, 2020·The Journal of Clinical Endocrinology and Metabolism·Ilhame DibounMohamed A Elrayess

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Software Mentioned

SPSS
R
SIMCA

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