Prevalence and predictors of pulmonary embolism in Korean patients with exacerbation of chronic obstructive pulmonary disease

Respiration; International Review of Thoracic Diseases
Keum-Ju ChoiTae-Hoon Jung

Abstract

Data concerning the rate of pulmonary embolism (PE) in Asian patients with chronic obstructive pulmonary disease (COPD) exacerbation are sparse, and no study has shown predictors of PE in these patients. The purpose of the present study was to investigate the prevalence and predictors of PE in Korean patients with COPD exacerbation. Hospitalized patients with COPD exacerbations were prospectively enrolled into this study and underwent computed tomography (CT) pulmonary angiography and indirect CT venography. The most common cause of COPD exacerbation was lower respiratory tract infection (82%; n = 84), followed by PE (5%; n = 5). Eight patients (8%) had venous thromboembolism, and deep vein thrombosis (DVT) was seen in 6%, with proximal DVT in 4%. On multivariate analysis, the absence of symptoms of respiratory infection and plasma D-dimer elevation (≥500 µg/l) were significant factors predicting PE in patients with COPD exacerbations (odds ratio 31, 95% confidence interval 2-563, p = 0.02, and odds ratio 25, 95% confidence interval 1-464, p = 0.03, respectively). PE comprises approximately 5% of the etiologies of COPD exacerbations in Koreans. The absence of symptoms suggestive of respiratory infection and elevated plasma D-di...Continue Reading

Citations

Jun 11, 2014·COPD·Maxime HackxPierre Alain Gevenois
Mar 31, 2016·Respirology : Official Journal of the Asian Pacific Society of Respirology·Fanny W KoIan A Yang
Mar 15, 2014·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Evrim Eylem AkpinarMeral Gülhan
Feb 2, 2016·The European Respiratory Journal·Mareike Lankeit, Matthias Held
Oct 13, 2020·Critical Reviews in Microbiology·Jiexing LiuZhangyong Song
Aug 12, 2020·The Clinical Respiratory Journal·Joaquín Maritano FurcadaBruno Leonel Ferreyro
Jun 3, 2021·Journal of Clinical Medicine·George KeramidasOurania S Kotsiou
Oct 9, 2021·Frontiers in Cellular and Infection Microbiology·Renyu RuanCaijuan Si

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.