Prevalence and profile of Neurodevelopment and Fetal Alcohol Spectrum Disorder (FASD) amongst Australian Aboriginal children living in remote communities

Research in Developmental Disabilities
James P FitzpatrickElizabeth J Elliott

Abstract

Despite multiple risk factors for neurodevelopmental vulnerability, few studies have assessed neurodevelopmental performance of Australian Aboriginal children. An important risk factor for neurodevelopmental vulnerability is prenatal alcohol exposure (PAE), which places children at risk for Fetal Alcohol Spectrum Disorder (FASD). This study assesses neurodevelopment outcomes in a population of Australian Aboriginal children with and without PAE. Children born in 2002/2003, and living in the Fitzroy Valley, Western Australia between April 2010 and November 2011, were eligible (N=134). Sociodemographic and antenatal data, including PAE, were collected by interview with 127/134 (95%) consenting parents/caregivers. Maternal/child medical records were reviewed. Neurodevelopment was assessed by clinicians blinded to PAE in 108/134 (81%) children and diagnoses on the FASD spectrum were assigned. Neurodevelopmental disorder was documented in 34/108 children (314.8 per 1000). Any diagnosis on the FASD spectrum was made in 21/108 (194.4 per 1000) children (95% CI=131.0-279.0). Neurodevelopmental impairment with or without PAE is highly prevalent among children in the Fitzroy Valley. Rates of diagnoses on the FASD spectrum are among the h...Continue Reading

Citations

Oct 9, 2018·Journal of Paediatrics and Child Health·Doug SheltonKaren Moritz
May 1, 2019·Health Research Policy and Systems·Babatope O AdebiyiAnna-Marie Beytell
Jun 13, 2020·Autism : the International Journal of Research and Practice·Rozanna LilleyElizabeth Pellicano
Jul 7, 2020·Australian and New Zealand Journal of Public Health·Martyn SymonsJames P Fitzpatrick
Mar 20, 2019·International Journal of Environmental Research and Public Health·Babatope O AdebiyiAnna-Marie Beytell
Jun 28, 2019·International Journal of Environmental Research and Public Health·Babatope O AdebiyiCharlene Erasmus
Oct 28, 2019·BMC Health Services Research·Philippa J DossetorAlexandra Lc Martiniuk
Feb 23, 2020·Journal of Developmental Origins of Health and Disease·Danielle J Burgess, Karen M Moritz
Jan 31, 2019·BMC Medical Ethics·Emily Fm FitzpatrickElizabeth J Elliott
Apr 11, 2018·BMJ Paediatrics Open·Tracey W TsangElizabeth J Elliott
Nov 27, 2020·The Journal of Applied Laboratory Medicine·Richard X Davey
Jun 29, 2021·American Journal of Obstetrics and Gynecology·Sarah E SteaneKaren M Moritz
Sep 1, 2021·Archives of public health = Archives belges de santé publique·Babatope O Adebiyi, Ferdinand C Mukumbang
Oct 31, 2021·Health Promotion Journal of Australia : Official Journal of Australian Association of Health Promotion Professionals·Donna LemonRebecca Anne Pedruzzi

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