Prevalence and risk factors for development of delirium in burn intensive care unit patients.

Journal of Burn Care & Research : Official Publication of the American Burn Association
Vivek AgarwalPratik P Pandharipande

Abstract

Delirium affects 60 to 80% of ventilated patients and is associated with worse clinical outcomes including death. Unfortunately, there are limited data regarding the prevalence and risk factors of delirium in critically ill burn patients. The objectives of this study were to evaluate the prevalence of delirium in ventilated burn patients, using validated instruments, and to identify its risk factors. Adult ventilated burn patients at two tertiary centers were prospectively evaluated for delirium using the Confusion Assessment Method in the Intensive Care Unit (CAM-ICU) for 30 days or until intensive care unit discharge. Patients with neurologic injuries, severe dementia, and those not expected to survive >24 hours were excluded. Markov logistic regression was used to identify the risk factors of delirium, adjusting for clinically relevant covariates. The 82 ventilated burn patients had a median (interquartile range) age of 48 (38-62) years, Acute Physiology and Chronic Health Evaluation II scores 27 (21-30), and percent burns of 20 (7-32). Prevalence of delirium was 77% with a median duration of 3 (1-6) days. Exposure to benzodiazepines was an independent risk factor for the development of delirium (odds ratio: 6.8 [confidence ...Continue Reading

References

May 1, 1979·British Journal of Anaesthesia·J W DundeeJ E Hegarty
Mar 1, 1988·The Journal of Burn Care & Rehabilitation·G K Stanford, R H Pine
Oct 1, 1985·Critical Care Medicine·W A KnausJ E Zimmerman
Nov 16, 1994·JAMA : the Journal of the American Medical Association·E R MarcantonioT H Lee
Apr 1, 1974·International Journal of Psychiatry in Medicine·N J Andreasen
Jun 13, 1998·Journal of General Internal Medicine·S K InouyeP Pompei
Nov 27, 1998·The American Journal of Medicine·E R MarcantonioT H Lee
Jan 23, 1999·Journal of Geriatric Psychiatry and Neurology·R C van der Mast
May 18, 2000·The New England Journal of Medicine·J P KressJ B Hall
Jun 3, 2000·Seminars in Clinical Neuropsychiatry·D J Meagher, P T Trzepacz
May 3, 2001·International Journal of Geriatric Psychiatry·T RahkonenR Sulkava
Jun 30, 2001·Intensive Care Medicine·N BergeronY Skrobik
Aug 9, 2001·British Journal of Anaesthesia·H M SolimanJ L Vincent
Aug 21, 2001·Intensive Care Medicine·M J DuboisY Skrobik
Jan 18, 2002·Intensive Care Medicine·E W ElyS K Inouye
Jan 22, 2002·Critical Care Medicine·J F PayenC Jacquot
Feb 6, 2002·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·UNKNOWN American College of Critical Care Medicine of the Society of Critical Care Medicine, American Society of Health-System Pharm
Feb 28, 2002·Archives of Internal Medicine·Jane McCuskerEric Belzile
Mar 21, 2002·Critical Care Medicine·Judith JacobiUNKNOWN Task Force of the American College of Critical Care Medicine (ACCM) of the Society of Critical Care Medicine (SCCM), America
Nov 8, 2002·American Journal of Respiratory and Critical Care Medicine·Curtis N SesslerR K Elswick
Feb 1, 2003·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·R Sean MorrisonAlbert L Siu
Jun 12, 2003·JAMA : the Journal of the American Medical Association·E Wesley ElyGordon R Bernard
Apr 9, 2004·Critical Care Medicine·Eric B MilbrandtE Wesley Ely
Apr 15, 2004·JAMA : the Journal of the American Medical Association·E Wesley ElyRobert S Dittus
Jul 22, 2004·Neuropsychology Review·James C JacksonE Wesley Ely
Jan 11, 2005·Critical Care Medicine·Shu-Min LinHan-Pin Kuo
Aug 10, 2005·Seminars in Respiratory and Critical Care Medicine·E W ElyS K Inouye
Mar 23, 2006·Journal of the American Geriatrics Society·Josh F PetersonE Wesley Ely
Nov 15, 2006·Intensive Care Medicine·Sébastien OuimetYoanna Skrobik
Jun 6, 2007·Intensive Care Medicine·Pratik PandharipandeE Wesley Ely
Dec 13, 2007·JAMA : the Journal of the American Medical Association·Pratik P PandharipandeE Wesley Ely
Feb 4, 2009·JAMA : the Journal of the American Medical Association·Richard R RikerUNKNOWN SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group
May 18, 2010·Critical Care Medicine·Timothy D GirardE Wesley Ely

❮ Previous
Next ❯

Citations

Jul 25, 2012·Critical Care Medicine·Christopher W SeymourTimothy D Girard
Oct 3, 2013·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Karin J Neufeld, Christine Thomas
Dec 29, 2012·Annals of Intensive Care·Rodrigo CavallazziPaul E Marik
Jul 30, 2014·Intensive & Critical Care Nursing : the Official Journal of the British Association of Critical Care Nurses·Christina Jones
Nov 28, 2012·Critical Care Clinics·Nathan E Brummel, Timothy D Girard
Jan 16, 2016·Annual Review of Medicine·Timothy D GirardE Wesley Ely
Oct 9, 2012·Best Practice & Research. Clinical Anaesthesiology·Giovanni MistralettiCesare Gregoretti
Oct 9, 2012·Best Practice & Research. Clinical Anaesthesiology·Christopher G HughesPratik P Pandharipande
Nov 15, 2011·Burns : Journal of the International Society for Burn Injuries·Steven E WolfBrett D Arnoldo
Sep 25, 2014·Critical Care Medicine·Irene J ZaalArjen J C Slooter
Dec 28, 2012·Critical Care Medicine·Juliana BarrUNKNOWN American College of Critical Care Medicine
Sep 26, 2015·Intensive Care Medicine·Irene J ZaalArjen J C Slooter
Mar 24, 2016·Journal of Palliative Medicine·Andrew Kamell, Lauren Kelley Smith
Jun 12, 2016·Journal of Critical Care·Jessica L ElefritzMichael R Lyaker
Jul 27, 2015·Intensive & Critical Care Nursing : the Official Journal of the British Association of Critical Care Nurses·Lisa Glynn, Margarita Corry
Apr 19, 2015·Journal of Critical Care·Bridgette L KramKelli R Brooks
May 2, 2015·Journal of Burn Care & Research : Official Publication of the American Burn Association·Andrew SingletonAmalia Cochran
Jan 31, 2016·BMJ Open·Domingo Palacios-CeñaCesar Fernández-de-las-Peñas
Jun 21, 2016·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Daniel A CaroffMichael Klompas
Jan 11, 2012·Journal of Intensive Care Medicine·Pierre N Azzam, Abdulkader Alam
Oct 19, 2016·Journal of Burn Care & Research : Official Publication of the American Burn Association·Yann-Leei Larry LeeJon D Simmons
Jun 10, 2014·Clinical Nurse Specialist CNS·Mallory Reimers, Catherine Miller
Aug 11, 2012·Journal of Burn Care & Research : Official Publication of the American Burn Association·Soman SenTina Palmieri
Oct 20, 2012·Journal of Burn Care & Research : Official Publication of the American Burn Association·G Morgan JonesClaire V Murphy
Oct 30, 2013·Journal of Burn Care & Research : Official Publication of the American Burn Association·Davin Kenneth Quinn
Feb 17, 2018·Journal of Intensive Care Medicine·Rima H BouajramJeremiah J Duby
Jan 25, 2018·The Annals of Pharmacotherapy·Joanna L StollingsMayur B Patel
Apr 17, 2015·The Cochrane Database of Systematic Reviews·Ken ChenShu Ming Pan
Jul 10, 2018·Critical Care Medicine·Lotte KokDieuwke S Veldhuijzen
Sep 21, 2018·Critical Care Medicine·Karla D KrewulakKirsten M Fiest
Dec 21, 2010·Current Opinion in Critical Care·Alessandro MorandiE Wesley Ely
Mar 23, 2019·Journal of Burn Care & Research : Official Publication of the American Burn Association·Taylor L PowellTam N Pham
Oct 12, 2011·Current Opinion in Critical Care·Frederick W Endorf, David Ahrenholz
Dec 25, 2013·Annals of the American Thoracic Society·S Jean HsiehMichelle N Gong
Sep 11, 2019·Journal of Burn Care & Research : Official Publication of the American Burn Association·Daan T van YperenCornelis H van der Vlies
Mar 19, 2019·Anesthesia and Analgesia·Kimberly F RengelChristopher G Hughes
Apr 9, 2011·Anesthesia and Analgesia·Christopher G Hughes, Pratik P Pandharipande
Feb 6, 2020·Anesthesia and Analgesia·Christopher G HughesUNKNOWN Perioperative Quality Initiative (POQI) 6 Workgroup

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.