Prevalence and risk factors for insomnia among breast cancer patients on aromatase inhibitors.

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
Krupali DesaiP R Gehrman

Abstract

Insomnia is increasingly recognized as a major symptom outcome in breast cancer; however, little is known about its prevalence and risk factors among women receiving aromatase inhibitors (AIs), a standard treatment to increase disease-free survival among breast cancer patients. A cross-sectional survey study was conducted among postmenopausal women with stage 0-III breast cancer receiving adjuvant AI therapy at an outpatient breast oncology clinic of a large university hospital. The insomnia severity index (ISI) was used as the primary outcome. Multivariate logistic regression analyses were performed to evaluate risk factors. Among 413 participants, 130 (31.5 %) had subthreshold insomnia on the ISI, and 77 (18.64 %) exceeded the threshold for clinically significant insomnia. In a multivariate logistic regression model, clinically significant insomnia was independently associated with severe joint pain (adjusted odds ratio (AOR) 4.84, 95 % confidence interval (CI) 1.71-13.69, P = 0.003), mild/moderate hot flashes (AOR 2.28, 95 % CI 1.13-4.60, P = 0.02), severe hot flashes (AOR 2.29, 95 % CI 1.23-6.81, P = 0.015), anxiety (AOR 1.99, 95 % CI 1.08-3.65, P = 0.027), and depression (AOR 3.57, 95 % CI 1.48-8.52, P = 0.004). Age (>65 v...Continue Reading

References

Nov 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·R J CouziJ H Fetting
Feb 7, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J Savard, C M Morin
Mar 20, 2001·American Journal of Respiratory and Critical Care Medicine·E O BixlerA Kales
Dec 4, 2001·The British Journal of Psychiatry : the Journal of Mental Science·A MykletunA A Dahl
Jun 13, 2002·Social Science & Medicine·Judith R DavidsonKarleen Schulze
Oct 23, 2002·The Breast Journal·Cheryl KoopmanDavid Spiegel
Oct 25, 2002·Psychology and Psychotherapy·Adam B SmithAnn Cull
Jan 28, 2003·Journal of Pain and Symptom Management·Barry V FortnerH Heith Durrence
Feb 5, 2004·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Rainer SimeitBeate Conta-Marx
Mar 12, 2004·The New England Journal of Medicine·R Charles CoombesUNKNOWN Intergroup Exemestane Study
May 29, 2004·Journal of Pain and Symptom Management·Josée SavardCharles M Morin
Sep 18, 2004·Psycho-oncology·Marie-Hélène SavardHans Ivers
Oct 30, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Lesley FallowfieldAnthony Howell
Dec 17, 2004·Behavioral Sleep Medicine·Lynne M TaylorCraig A White
Jul 13, 2005·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Sonia Ancoli-IsraelLavinia Fiorentino
Sep 19, 2006·American Journal of Surgery·Jennifer R GarreauNathalie Johnson
Nov 23, 2006·The Psychiatric Clinics of North America·Chien-Ming YangPaul Glovinsky
Apr 13, 2007·Psycho-oncology·Wayne A BardwellUNKNOWN Women's Healthy Eating & Living (WHEL) Study Group
Jan 27, 2009·Journal of Behavioral Medicine·Matthew R Ebben, Arthur J Spielman
Sep 16, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Rowan T Chlebowski
Oct 17, 2009·The Journal of Steroid Biochemistry and Molecular Biology·Jürgen Geisler, Per E Lønning
Jul 14, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Harold J BursteinUNKNOWN American Society of Clinical Oncology

❮ Previous
Next ❯

Citations

Dec 10, 2013·International Journal of Behavioral Medicine·Sara VargasRobert P DerHagopian
Feb 13, 2016·Breast Cancer Research and Treatment·Alice C ShapiroRachel E Lerner
Oct 29, 2014·Menopause : the Journal of the North American Menopause Society·Hrayr AttarianBarbara Phillips
Oct 14, 2014·The Breast : Official Journal of the European Society of Mastology·Ana Rute CostaNuno Lunet
Aug 16, 2016·Journal of Pain and Symptom Management·Yuping WangJincai He
Dec 6, 2016·Palliative & Supportive Care·Philip R GehrmanJun Mao
Apr 7, 2017·The Breast : Official Journal of the European Society of Mastology·Filipa FontesNuno Lunet
Jan 25, 2017·The Breast Journal·Noelia Galiano-CastilloIrene Cantarero-Villanueva
Apr 24, 2018·Oncology Nursing Forum·Janine OvercashAnne M Noonan
Mar 5, 2014·Asian Journal of Andrology·Julia LipianskayaJiaoti Huang
Oct 10, 2014·The Cancer Journal·Mellar P Davis, Harold W Goforth
Oct 10, 2014·The Cancer Journal·J Keith Mansel, Elise C Carey
Jun 18, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Filipa FontesNuno Lunet
Sep 30, 2020·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Kerry EttridgeCaroline Miller
Apr 30, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Filipa FontesNuno Lunet
Jul 28, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Laurence LeysenDavid Beckwée
Aug 24, 2018·Cancer Nursing·Yehui ZhuCatherine M Bender
Apr 22, 2020·Breast Cancer Research and Treatment·Agnes KwakJeffrey Peppercorn
Sep 12, 2020·Breast Cancer Research and Treatment·Cathleen Y XingAdana A M Llanos
Jan 30, 2021·BMJ Supportive & Palliative Care·Amira DaldoulOlfa Zoukar
Apr 13, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Emma-Kate CarsonBelinda E Kiely
Jul 11, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Susan GraysonSusan Wesmiller

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