Prevalence and risk factors for trimethoprim-sulfamethoxazole-resistant Escherichia coli among women with acute uncomplicated urinary tract infection in a developing country

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Louie Mar GangcuangcoMediadora Saniel

Abstract

Prospective studies from developing countries that have investigated risk factors for trimethoprim-sulfamethoxazole (TMP-SMX)-resistant Escherichia coli in women with uncomplicated urinary tract infection (UTI) remain scarce. Women with acute uncomplicated UTI were enrolled prospectively. Urine was sent for antimicrobial susceptibility testing. Logistic regression analysis was used to identify risk factors for TMP-SMX resistance. Of 405 participants, 229 (56.5%) had bacteriuria (mean age 31.9 ± 9.5 years). In the previous 12 months, 77 (33.6%) had experienced at least one UTI episode and 106 (46.3%) reported antimicrobial use. The most common uropathogens were E. coli (75.8%) and Staphylococcus saprophyticus (8.9%). For the 179 E. coli, resistance rates were highest for ampicillin (64.3%) and TMP-SMX (41.3%). Resistance to cephalosporins, nitrofurantoin, and fluoroquinolones was much lower compared with the hospital laboratory-based surveillance data. Risk factors for TMP-SMX resistance were UTI in the last 6 months (odds ratio 2.22; p = 0.04) and the number of UTI episodes in the past year (odds ratio 2.06; p = 0.004). The number of UTI episodes (adjusted odds ratio 2.21; p = 0.02) remained significant on multivariate analysis...Continue Reading

References

Apr 1, 1990·Antimicrobial Agents and Chemotherapy·B E MurrayR R Reves
Oct 28, 1998·Japanese Journal of Medical Science & Biology·J IqbalM Rahman
Aug 10, 1999·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·A BaerheimS Hunskaar
Jun 5, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·K GuptaW E Stamm
Mar 27, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Patricia D BrownBetsy Foxman
Mar 26, 2003·The Journal of Antimicrobial Chemotherapy·Joshua P MetlayDavid A Asch
Jun 19, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas M HootonLindsay E Nicolle
Aug 11, 2004·Mayo Clinic Proceedings·Loren G Miller, Angela W Tang
May 14, 2005·The Journal of Antimicrobial Chemotherapy·Jacques Albert DromignyJean David Perrier-Gros-Claude
Jul 29, 2005·The Lancet Infectious Diseases·Iruka N OkekeKeith P Klugman
Sep 22, 2005·The Journal of Antimicrobial Chemotherapy·Hande ArslanUNKNOWN Urinary Tract Infection Study Group
Mar 24, 2007·Annals of Clinical Microbiology and Antimicrobials·Mohammed AkramAsad U Khan
Jun 2, 2007·The Journal of Antimicrobial Chemotherapy·Sharon HillierStephen Palmer
Dec 19, 2007·Antimicrobial Agents and Chemotherapy·Richard ColganKalpana Gupta
Apr 18, 2008·The Journal of Antimicrobial Chemotherapy·Sita NysUNKNOWN Susceptibility Surveillance Study Group
Sep 24, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·David A TalanUNKNOWN EMERGEncy ID NET Study Group
May 5, 2010·Journal of Infection in Developing Countries·Nasim KashefSahba Shahbazi
Jun 19, 2010·International Urology and Nephrology·Sônia M H A AraújoElizabeth F Daher
Dec 3, 2010·The Journal of Antimicrobial Chemotherapy·Willize E van der StarreJaap T van Dissel
Jan 29, 2011·Lancet·Richard J CokerPiya Hanvoravongchai
Jul 19, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Guillermo V SanchezJose Bordon
Aug 11, 2011·The European Respiratory Journal·D FalzonM Zignol
Nov 8, 2011·International Journal of Antimicrobial Agents·Gunnar Kahlmeter, Hanna Odén Poulsen
Jan 22, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·James S MoltonDale A Fisher
Nov 23, 2013·Infection & chemotherapy·Cheol-In Kang, Jae-Hoon Song

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Citations

Jan 28, 2016·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Louie Mar GangcuangcoMediadora Saniel
Jan 15, 2016·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·S Christian Smith, Daniel R Martin
Mar 28, 2020·PloS One·Natalia C S CostaEduardo M Cilli
Aug 2, 2019·International Journal of Antimicrobial Agents·Marissa D MalchioneJesse L Goodman

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