Prevalence and risk factors for upper gastrointestinal diseases in health check-up subjects: a nationwide multicenter study in Korea

Scandinavian Journal of Gastroenterology
Kwangwoo NamNayoung Kim

Abstract

The prevalence of upper gastrointestinal disease is expected to change following advances in socioeconomic status and improved hygiene in Korea. The aim of this study was to investigate the recent trends in upper gastrointestinal diseases based on endoscopic findings and Helicobacter pylori (H. pylori) seroprevalence in subjects undergoing health check-up at tertiary centers in Korea. A multicenter cross-sectional study was conducted at nine healthcare centers between September 2016 and June 2017. The subjects were evaluated using questionnaires, upper endoscopy and H. pylori serology tests. The results were compared with previous data in our study group obtained from eight tertiary healthcare centers in 2011 (n = 4023). In total, we prospectively enrolled 2504 subjects undergoing health check-up. The prevalence of reflux esophagitis (RE) was 9.7%, which showed an increasing but insignificant trend since 2011 (8.8%). The prevalence of active and healing-stage benign gastric ulcer and duodenal ulcer (DU) was 1.6% and 1.2%, respectively, which confirmed a significant decrease since 2011 (4.1%; p < .001 and 2.2%; p = .005, respectively). The prevalence of gastric cancer was 0.5%, representing an increasing trend since 2011 (0.12%;...Continue Reading

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Citations

Jun 26, 2018·Journal of Neurogastroenterology and Motility·Sung Eun KimSuck Chei Choi
Sep 6, 2019·Helicobacter·Doron BoltinChristian Schulz
Sep 6, 2019·Helicobacter·Mārcis LejaChristoph Steininger
May 1, 2021·Journal of Clinical Medicine·Sung-Goo KangSung Hoon Jung
Jul 3, 2021·International Journal of Environmental Research and Public Health·Eunchan MunSoyoung Park

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