Prevalence and treatment outcomes of routine Chlamydia trachomatis , Neisseria gonorrhoeae and Trichomonas vaginalis testing during antenatal care, Gaborone, Botswana

Sexually Transmitted Infections
Adriane WynnChelsea Morroni

Abstract

Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Trichomonas vaginalis (TV) are curable, mostly asymptomatic, STIs that cause adverse maternal and perinatal outcomes. Most countries do not test for those infections during antenatal care. We implemented a CT, NG and TV testing and treatment programme in an antenatal clinic in Gaborone, Botswana. We conducted a prospective study in the antenatal clinic at Princess Marina Hospital in Gaborone, Botswana. We offered pregnant women who were 18 years or older and less than 35 weeks of gestation, CT, NG and TV testing using self-collected vaginal swabs. Testing was conducted using a GeneXpert® CT/NG and TV system. Those who tested positive were given directly observed antibiotic therapy and asked to return for a test of cure. We determined the prevalence of infections, uptake of treatment and proportion cured. The relationships between positive STI test and participant characteristics were assessed. We enrolled 400 pregnant women. Fifty-four (13.5%) tested positive for CT, NG and/or TV: 31 (8%) for CT, 5 (1.3%) for NG and 21 (5%) for TV. Among those who tested positive, 74% (40) received same-day, in person results and treatment. Among those who received delayed results (6), ...Continue Reading

References

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Citations

Jun 6, 2020·Expert Review of Molecular Diagnostics·Charlotte A Gaydos, Johan H Melendez
Jan 10, 2019·Journal of the Pediatric Infectious Diseases Society·Melissa S NolanTim Erickson
Aug 7, 2019·Bulletin of the World Health Organization·Jane RowleyMelanie M Taylor
Jun 27, 2021·Sexually Transmitted Diseases·Tembe Carveth-JohnsonChelsea Morroni
Dec 18, 2021·Southern African Journal of Infectious Diseases·Bongekile Ngobese, Nathlee S Abbai

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