Abstract
To determine the prevalence and the diversity of extended-spectrum beta-lactamases (ESBLs) among Escherichia coli isolates in Zhengzhou, China. Clinical isolates were collected and investigated from the first affiliated hospital of Zhengzhou University and its associated health-care facilities in Zhengzhou, China, during the period from January 2006 to June 2008. Antibiograms were performed on Mueller-Hinton agar plates with the disc-diffusion method and MICs were determined by the agar-dilution method. Total DNA was extracted with a Qiagen mini kit and screened by PCR. Of 94 nonduplicate ESBL-positive isolates, TEM-type was encoded in 74 and 79% of the ESBL isolates. Fifty-six isolates were SHV type ESBLs. CTX-M-1, CTX-M-14, CTX-M-25, and CTX-M-38 types were encoded in 30, 54, 6, and 4, respectively. OXA-1-type beta-lactamases were encoded in six and OXA-20-type was encoded in two isolates. We describe a complex ESBL epidemiology. The study revealed a high rate of ESBL-producing E. coli isolates. TEM and CTX-M enzymes dominated in ESBL-positive E. coli isolates in Zhengzhou, China.
References
Oct 23, 1997·Antimicrobial Agents and Chemotherapy·H VahabogluM Otkun
Apr 29, 1998·Antimicrobial Agents and Chemotherapy·M GniadkowskiA Bauernfeind
Oct 19, 2000·Antimicrobial Agents and Chemotherapy·C De ChampsJ Sirot
Jan 4, 2001·Journal of Clinical Microbiology·D GirlichP Nordmann
Apr 26, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P L WinokurN Legakis
Jul 14, 2001·Antimicrobial Agents and Chemotherapy·R BonnetJ Sirot
Aug 17, 2002·Antimicrobial Agents and Chemotherapy·Christophe De ChampsPatrice Nordmann
Nov 19, 2002·Antimicrobial Agents and Chemotherapy·Van CaoPatrice Courvalin
Jan 25, 2003·Antimicrobial Agents and Chemotherapy·Isabelle CasinEkkehard Collatz
Dec 25, 2003·Antimicrobial Agents and Chemotherapy·R Bonnet
Jul 30, 2004·The Journal of Antimicrobial Chemotherapy·C De ChampsJ Sirot
Sep 7, 2004·The Journal of Antimicrobial Chemotherapy·N WoodfordD M Livermore
Jun 22, 2005·The Journal of Antimicrobial Chemotherapy·Thierry NaasPatrice Nordmann
Mar 16, 2006·The Journal of Antimicrobial Chemotherapy·Katherine J GrayC Anthony Hart
Apr 20, 2006·International Journal of Antimicrobial Agents·Abdelaziz TouatiChristophe de Champs
Jun 28, 2006·Antimicrobial Agents and Chemotherapy·M LavollayG Arlet
Jul 18, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Z SaribasA Pinar
Aug 1, 2006·Trends in Microbiology·David M Livermore, Neil Woodford
Sep 1, 2006·Current Opinion in Microbiology·Rafael Cantón, Teresa M Coque
Sep 8, 2006·Journal of Clinical Microbiology·Kelthoum MamloukGuillaume Arlet
Sep 22, 2006·Journal of Clinical Microbiology·Nadjia Ramdani-BouguessaManuela Caniça
Apr 4, 2008·The Journal of Antimicrobial Chemotherapy·Hassen IabadeneGuillaume Arlet
Citations
Feb 2, 2011·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Umaer Naseer, Arnfinn Sundsfjord
Oct 11, 2012·PloS One·Jascha VervoortUNKNOWN SATURN WP1 study groups
Mar 5, 2016·Frontiers in Microbiology·Mudsser AzamQazi M R Haq
Jan 17, 2015·Annals of Clinical Microbiology and Antimicrobials·Huiqing ShiPeiyuan Xia
Sep 2, 2016·Japanese Journal of Infectious Diseases·Xiaobing GuoYihui Ren
Apr 28, 2012·FEMS Microbiology Letters·Shuchang AnZhancheng Gao
Oct 5, 2016·Letters in Applied Microbiology·M-Y WangC-J Hu