Prevalence, Clinical Presentation, and Outcome of Tuberculosis in Patients with Chronic Kidney Disease at a Tertiary Care Hospital in Nepal

International Journal of Nephrology
Ravi Ranjan Pradhan, Mahesh Raj Sigdel

Abstract

Tuberculosis (TB) is a serious public health threat in low- and middle-income countries like Nepal. Chronic kidney disease (CKD) patients are at higher risk of developing new infection as well as reactivation of TB. We aimed to determine the prevalence, clinical presentations, and outcome of TB in patients with CKD in Nepal. A hospital-based cross-sectional study was performed at Tribhuvan University Teaching Hospital (TUTH), a tertiary level referral centre in Kathmandu, Nepal. We included patients older than 16 years with the diagnosis of CKD stage 3, 4, 5, and 5D (CKD 5 on maintenance dialysis); renal transplant recipients and patients living with HIV/AIDS were excluded. Tuberculosis was diagnosed based on clinical, radiological, and laboratory findings. Prior written informed consent was obtained. Approval was obtained from the Institutional Review Board of the Institute of Medicine. Data entry and statistical analysis were performed using SPSS v21. A total of 401 patients with CKD were included in the study (mean age, 50.92 ± 17.98 years; 64.8% male). The prevalence of TB in CKD patients was found to be 13.7% (55), out of which 49 were newly diagnosed cases. The most common clinical presentations of TB in CKD were anorexia...Continue Reading

References

Jan 23, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Anne WautersBart D Maes
Feb 8, 2006·Arthritis and Rheumatism·Susan S JickHyon K Choi
Sep 14, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Mary M KloteKevin C Abbott
Feb 5, 2008·International Journal of Epidemiology·Kelechi E Nnoaham, Aileen Clarke
Oct 15, 2008·Revista Da Sociedade Brasileira De Medicina Tropical·Florian H Pilsczek, Stefan H E Kaufmann
May 6, 2009·Annals of Internal Medicine·Andrew S LeveyUNKNOWN CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
Nov 10, 2009·BMC Nephrology·Antonios I ChristopoulosGeorge A Barbalias
Aug 16, 2011·Lancet·Andrew S Levey, Josef Coresh
Nov 1, 2011·Nigerian Journal of Clinical Practice·O A AdegboyeN J Sajo
Jun 4, 2013·Lancet·Vivekanand JhaChih-Wei Yang
Sep 21, 2013·Indian Journal of Nephrology·T Manmadha RaoK V Dakshinamurty
May 28, 2014·Revista Da Sociedade Brasileira De Medicina Tropical·Aucely Corrêa Fernandes ChagasMaria Ilizabeth Donatti
May 15, 2016·Kidney International·Kamila RomanowskiJames C Johnston
Jan 18, 2017·Drug Design, Development and Therapy·Shao-Jun HuangShao-Fa Xu
May 14, 2017·The Lancet Infectious Diseases·Aditya SharmaUNKNOWN Global Preserving Effective TB Treatment Study Investigators

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Methods Mentioned

BETA
PCR

Software Mentioned

SPSS

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