Abstract
The proportion of women who have already been exposed to human papillomavirus (HPV) infection by the time they first become pregnant, and the influence of pregnancy and delivery on the course of HPV infection are unclear. In Kampala, Uganda, 987 young primiparous pregnant women aged <25 years had gynaecological examination and liquid-based cytology. In the follow-up, women acted as their own controls, i.e., 1st/2nd versus 3rd trimesters (105 women), and during pregnancy versus after delivery (289 women). HPV was assessed using highly sensitive PCR assays. Prevalence of HPV and HIV infections at baseline were 60.0% and 7.3%, respectively. HPV16 and 18 were detected in 8.4% and 5.8%, respectively, i.e., less frequently than HPV51 (8.7%) and 52 (12.1%). At follow-up new HPV infections were detected in 42.9% of women between the 1st/2nd and 3rd trimesters, and 38.1% between pregnancy and delivery, but 50.4% and 71.8% of HPV infections, respectively, cleared, leaving HPV prevalence unchanged in the different periods. Prevalence of cytological abnormalities diminished after delivery (from 21.2% to 12.4%). Presence of genital warts and sexually transmitted infections other than HPV were the strongest risk factors for prevalent or inci...Continue Reading
References
May 1, 1992·Journal of Clinical Pathology·B S HoS I Egglestone
Apr 1, 1990·American Journal of Perinatology·T C PengT R Johnson
Mar 1, 1996·Gynecologic Oncology·J Chang-ClaudeL Turek
May 1, 1996·American Journal of Obstetrics and Gynecology·K H FifeR Hansell
Mar 21, 1998·American Journal of Obstetrics and Gynecology·S SethiJ Chang-Claude
Aug 15, 1998·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·R G DowningM A Rayfield
Dec 10, 1998·The American Journal of Pathology·B KleterW Quint
Jul 16, 1999·Journal of Clinical Microbiology·B KleterW Quint
Apr 23, 2002·JAMA : the Journal of the American Medical Association·Diane SolomonUNKNOWN Bethesda 2001 Workshop
Jun 27, 2002·British Journal of Cancer·M A E NobbenhuisC J L M Meijer
Jul 13, 2002·Journal of Medical Virology·Paul K S ChanAugustine F Cheng
Jul 3, 2003·British Journal of Cancer·P SasieniJ Cuzick
Jun 16, 2004·International Journal of Cancer. Journal International Du Cancer·Nubia MuñozChris J L M Meijer
Oct 4, 2005·The Journal of Steroid Biochemistry and Molecular Biology·René Druckmann, Marc-Alexandre Druckmann
Oct 6, 2005·Sexually Transmitted Diseases·Carlos Hernández-GirónJorge Salmerón
Mar 30, 2006·International Journal of Cancer. Journal International Du Cancer·UNKNOWN International Collaboration of Epidemiological Studies of Cervical Cancer
Oct 3, 2006·Obstetrics and Gynecology·Howard MinkoffHoward Strickler
Nov 23, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Salvatore VaccarellaSilvia Franceschi
Apr 18, 2007·Clinical and Experimental Immunology·J DillnerL Dillner
Sep 11, 2007·Lancet·Mark SchiffmanSholom Wacholder
Sep 18, 2007·The Journal of Molecular Diagnostics : JMD·Koen D QuintWim G V Quint
Nov 13, 2007·Lancet·UNKNOWN International Collaboration of Epidemiological Studies of Cervical CancerSiân Sweetland
Nov 21, 2007·Bulletin of the World Health Organization·F T CuttsL Markowitz
Feb 2, 2008·The Journal of Infectious Diseases·Cecily BanuraElisabete Weiderpass
Citations
Aug 31, 2010·Archives of Gynecology and Obstetrics·Miodrag MilojkovicBojana Vujic Vakanjac
Dec 21, 2010·Archives of Gynecology and Obstetrics·Gintautas DomžaGražina Drąsutienė
Sep 10, 2013·BMC Pregnancy and Childbirth·GeumJoon ChoHaiJoong Kim
Apr 14, 2012·Virology Journal·Hyun ParkTae Jin Kim
Apr 13, 2010·Infectious Agents and Cancer·Cecily BanuraElisabete Weiderpass
Jul 14, 2011·Infectious Agents and Cancer·Cecily BanuraFred M Wabwire
Jul 12, 2013·Infectious Agents and Cancer·Cecily BanuraEdward K Mbidde
Jun 8, 2011·BMC Research Notes·Proscovia B NamujjuMatti Lehtinen
Mar 15, 2013·Sexually Transmitted Infections·Deborah Watson-JonesSilvia de Sanjosé
Jun 14, 2013·Sexually Transmitted Infections·Pascale LissoubaBertran Auvert
Dec 6, 2012·Journal of Women's Health·Channa E SchmeinkRuud L M Bekkers
Feb 26, 2010·Scandinavian Journal of Infectious Diseases·Proscovia Bazanya NamujjuMatti Lehtinen
Aug 2, 2011·Infectious Diseases in Obstetrics and Gynecology·Bertran AuvertAnna-Lise Williamson
Dec 30, 2015·BioMed Research International·Mariusz SkoczyńskiAnna Kwaśniewska
Sep 15, 2010·International Journal of Cancer. Journal International Du Cancer·Marko MerikukkaMatti Lehtinen
Feb 15, 2011·Birth Defects Research. Part A, Clinical and Molecular Teratology·Tonia C CarterUNKNOWN National Birth Defects Prevention Study
Jul 3, 2013·The Journal of Obstetrics and Gynaecology Research·Yun Hwan KimYong Sang Song
May 21, 2015·Archives of Gynecology and Obstetrics·Mila M B P SalcedoGustavo Py Gomes da Silveira
Oct 9, 2015·BMC Pregnancy and Childbirth·Helen TrottierUNKNOWN Ludwig-McGill Cohort Study Group
Aug 13, 2011·The Journal of General Virology·P B NamujjuM Lehtinen
Dec 3, 2013·BMC Infectious Diseases·Emilia Moreira JalilSilvana Maria Quintana
Jan 10, 2013·PloS One·Karolina LouvantoStina Syrjänen
Aug 3, 2016·PloS One·Edward KumakechSören Andersson
Jan 26, 2018·AIDS·Gui LiuRuanne V Barnabas
Feb 11, 2011·Journal of Human Genetics·Kentaro YamasakiHideaki Masuzaki
Jun 7, 2018·Journal of the International AIDS Society·Katharine J LookerMarie-Claude Boily
Feb 18, 2010·Epidemiology·David C SokalNguyen Dinh Loan
Jun 13, 2019·Sexually Transmitted Diseases·Joseph VyankandonderaStanley Luchters
Feb 6, 2020·The Journal of Infectious Diseases·Joseph NiyibiziHelen Trottier
Jun 10, 2018·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Luciana Bueno de FreitasLiliana Cruz Spano
Sep 20, 2018·Journal of Biomedical Science·Nádia Calvo Martins OkuyamaKaren Brajão de Oliveira
May 26, 2018·PloS One·Chloe A TeasdaleHeidi E Jones
Jul 25, 2020·Annals of Global Health·Alfred JathoNoleb Mugume Mugisha
Jul 12, 2019·Sexually Transmitted Diseases·Joseph VyankandonderaStanley Luchters
Aug 6, 2021·Risk Management and Healthcare Policy·Dandan LuoBinhua Dong