Atrial fibrillation (AF) is the most common of the serious cardiac rhythm disturbances and is responsible for substantial morbidity and mortality in the general population. Its prevalence doubles with each advancing decade of age, from 0.5% at age 50-59 years to almost 9% at age 80-89 years. It is also becoming more prevalent, increasing in men aged 65-84 years from 3.2% in 1968-1970 to 9.1% in 1987-1989. This statistically significant increase in men was not explained by an increase in age, valve disease, or myocardial infarctions in the cohort. The incidence of new onset of AF also doubled with each decade of age, independent of the increasing prevalence of known predisposing conditions. Based on 38-year follow-up data from the Framingham Study, men had a 1.5-fold greater risk of developing AF than women after adjustment for age and predisposing conditions. Of the cardiovascular risk factors, only hypertension and diabetes were significant independent predictors of AF, adjusting for age and other predisposing conditions. Cigarette smoking was a significant risk factor in women adjusting only for age (OR = 1.4), but was just short of significance on adjustment for other risk factors. Neither obesity nor alcohol intake was asso...Continue Reading
Associated Clinical Trials
Predictive Factors to Effectively Terminate Paroxysmal Atrial Fibrillation by Blocking Atrial Selective Ionic Currents
Warfarin in the prevention of stroke associated with nonrheumatic atrial fibrillation. Veterans Affairs Stroke Prevention in Nonrheumatic Atrial Fibrillation Investigators
Incidence and prognostic significance of chronic atrial fibrillation among 5,839 consecutive patients with acute myocardial infarction. The SPRINT Study Group. Secondary Prevention Reinfarction Israeli Nifedipine Trial
Prognostic guides in patients with idiopathic or ischemic dilated cardiomyopathy assessed for cardiac transplantation
The effect of low-dose warfarin on the risk of stroke in patients with nonrheumatic atrial fibrillation
Placebo-controlled, randomised trial of warfarin and aspirin for prevention of thromboembolic complications in chronic atrial fibrillation. The Copenhagen AFASAK study
Echocardiographic assessment of left ventricular diastolic performance in hypertensive subjects. Correlation with changes in left ventricular mass
Prevalence, age distribution, and gender of patients with atrial fibrillation. Analysis and implications
Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study
Prognostic factors in first-ever stroke in the carotid artery territory seen within 6 hours after onset
Atrial fibrillation in the setting of acute myocardial infarction: the GUSTO-I experience. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries
A variant of IL6R is associated with the recurrence of atrial fibrillation after catheter ablation in a Chinese Han population
Cost-effectiveness of different strategies for stroke prevention in patients with atrial fibrillation in a health resource-limited setting
Efficacy and safety of radiofrequency catheter ablation for atrial fibrillation in chronic hemodialysis patients
Sexual dimorphism in rat aortic endothelial function of streptozotocin-induced diabetes: possible involvement of superoxide and nitric oxide production
Diagnosis and management of atrial fibrillation by primary care physicians in Italy : a retrospective, observational analysis.
Left atrial appendage exclusion for prevention of stroke in atrial fibrillation: review of minimally invasive approaches
Depression in paroxysmal and persistent atrial fibrillation patients: a cross-sectional comparison of patients enroled in two large clinical trials
Rivaroxaban versus warfarin in Japanese patients with non-valvular atrial fibrillation in relation to hypertension: a subgroup analysis of the J-ROCKET AF trial
A cohort study examination of established and emerging risk factors for atrial fibrillation: the Busselton Health Study
WatchBP Home A for opportunistically detecting atrial fibrillation during diagnosis and monitoring of hypertension: a NICE Medical Technology Guidance.
Atrial fibrillation as manifestation and consequence of underlying cardiomyopathies: from common conditions to genetic diseases
Relation of systolic, diastolic, and pulse pressures and aortic distensibility with atrial fibrillation (from the Multi-Ethnic Study of Atherosclerosis)
Obese hypertensive men have plasma concentrations of C-reactive protein similar to that of obese normotensive men
Incidence and predictors of atrial fibrillation and its impact on long-term survival in patients with supraventricular arrhythmias
Relation of atrial fibrillation (AF) and change of lipoproteins: male patients with AF exhibited severe pro-inflammatory and pro-atherogenic properties in lipoproteins
Catheter ablation of atrial fibrillation: randomized controlled trials and registries, a look back and the view forward
N-terminal pro B-type natriuretic peptide levels predict newly detected atrial fibrillation in a population-based cohort
Screening for atrial fibrillation in general practice: a national, cross-sectional study of an innovative technology
Prevalence of atrial fibrillation and its associated factors in Spain: An analysis of 6 population-based studies. DARIOS Study.
What are the initial perceptions of multidisciplinary personnel new to integrated care pathway development?
Genome-wide linkage scan identifies a novel genetic locus on chromosome 5p13 for neonatal atrial fibrillation associated with sudden death and variable cardiomyopathy
A role for CETP TaqIB polymorphism in determining susceptibility to atrial fibrillation: a nested case control study
Early electrical remodeling in rabbit pulmonary vein results from trafficking of intracellular SK2 channels to membrane sites
Angiotensin II receptor blockers and cardiovascular protection: focus on left ventricular hypertrophy regression and atrial fibrillation prevention
Physical activity and incidence of atrial fibrillation in older adults: the cardiovascular health study
Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.
Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.
Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.
Cardiovascular Diseases: Risk Factors
Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.