Prevalence of age-related macular degeneration in Latinos: the Los Angeles Latino eye study

Ophthalmology
Rohit VarmaLos Angeles Latino Eye Study Group

Abstract

To estimate the age- and gender-specific prevalence of early age-related macular degeneration (AMD; drusen and retinal pigmentary abnormalities) and advanced AMD (exudative AMD and geographic atrophy) in Latinos. Population-based, cross-sectional study. Six thousand three hundred fifty-seven Latinos 40 years and older from 6 census tracts in Los Angeles, California. The study cohort consisted of self-identified Latinos 40 years and over. Participants underwent a complete ophthalmologic examination, including stereoscopic macular photographs. Photographs were graded using a modified Wisconsin Age-Related Maculopathy Grading System. Prevalence of early AMD, drusen, geographic atrophy, and exudative AMD. Of the 7789 eligible subjects, 6357 participants (82%) completed an interview and clinical examination, and 5875 (75%) had gradable photographs. Prevalence of advanced AMD increased from 0% in those 40-49 years of age to 8.5% in those 80 or older; that of early AMD from 6.2% to 29.7%, that of retinal pigment abnormalities from 4.1% to 19.3%, that of large drusen (> or =125 microm in diameter) from 8.5% to 45.3%, that of soft drusen from 15.4% to 58.1%, and that of soft indistinct drusen from 3.6% to 30.8%. The prevalence of early ...Continue Reading

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Citations

Jun 16, 2010·Archives of Ophthalmology·Ronald KleinBarbara E K Klein
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Aug 8, 2006·Ophthalmology·Rohit VarmaUNKNOWN Los Angeles Latino Eye Study Group
Nov 18, 2005·Ophthalmology·M Cristina LeskeUNKNOWN Barbados Eye Studies Group

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