Prevalence of allergic sensitization, hay fever, eczema, and asthma in a longitudinal birth cohort

Journal of Asthma and Allergy
Louisa OwensPeter N Le Souëf

Abstract

The aim of this study was to longitudinally assess the prevalence of allergic sensitization, asthma, eczema and hay fever from infancy to adulthood in a single cohort. This prospective study is based on a longitudinal birth cohort of 253 participants, with respiratory and immunological assessments at 1, 6, 11, 18 and 24 years of age. Subjects were recruited from an urban maternity hospital. Retention rates varied from 45% to 72% at follow-up assessments. Asthma diagnosis was based on physician diagnosis of asthma and symptoms/medications in the previous 12 months. Allergic sensitization was defined by the positive skin prick test. Hay fever and eczema were based on a questionnaire. The prevalence of allergic sensitization rose from 19% (n=33) at 1 year of age to 71% (n=77) at 24 years of age. The rate of asthma halved from 25% at 6 years of age to 12%-15% between 11 and 24 years of age, but the prevalence of allergic sensitization among those with asthma doubled from 50% at 6 years of age to 100% at 24 years of age. Hay fever rates rose throughout childhood from 7% at 6 years of age to 44% at 24 years of age, while the prevalence of eczema reduced from 25% at 6 years of age to 16% at 24 years of age. Parental atopy doubled the ...Continue Reading

Citations

Nov 6, 2018·Current Opinion in Allergy and Clinical Immunology·René Maximiliano GómezGiorgio W Canonica
Aug 9, 2020·Journal of Cutaneous Pathology·Su-Lin ChanNima Mesbah Ardakani
Mar 17, 2020·Journal of Health & Pollution·Uttam Paudel, Krishna Prasad Pant
May 18, 2020·The Journal of Allergy and Clinical Immunology·Shyam S MohapatraRyan Green
Mar 27, 2019·La Presse médicale·Bénédicte LeynaertRaphaëlle Varraso
Apr 26, 2021·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Marianna KarachaliouManolis Kogevinas

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