Prevalence of anal human papillomavirus infection and anal cytologic abnormalities in HIV-seropositive women

AIDS
P HillemannsT C Wright

Abstract

To determine the prevalence of anal human papillomavirus (HPV) infections and anal cytologic abnormalities in HIV-seropositive and HIV-seronegative women. This cross-sectional study of a cohort of women with known HIV serostatus involved a standardized interview and a gynecologic examination, including a cytologic evaluation of the cervix and anus. Anal swabs were tested for HPV DNA using the Hybrid Capture assay. Two HIV/AIDS clinics, a sexually transmitted disease clinic, a methadone clinic and women enrolled in a study of HIV heterosexual transmission in the greater New York City metropolitan area. One hundred and two HIV-seropositive and 96 HIV-seronegative women were selected from an ongoing study of the gynecologic manifestations of HIV infection. Detection of anal HPV DNA and anal cytologic abnormalities. Anal cytologic abnormalities were detected in 27 (26%) of the 102 HIV-seropositive women and in six (7%) of 96 HIV-seronegative women. Five (5%) of the anal smears from the HIV-seropositive women and one (1%) from the HIV-seronegative women had low-grade anal intra-epithelial neoplasia. The remainder of the anal cytologic abnormalities were classified as mild squamous cytologic atypia. HPV DNA was detected in 30 (29%) o...Continue Reading

Citations

May 2, 2000·Diseases of the Colon and Rectum·D J BrowseJ Nevin
Jun 26, 1998·Progress in Lipid Research·I Ishizuka
Nov 14, 1997·The New England Journal of Medicine·X W SunT C Wright
Sep 8, 2012·Sexual Health·François CoutléeEduardo L Franco
Jun 17, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Elizabeth Y ChiaoHashem El Serag
Feb 21, 2007·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Yolan BandaBenjamin H Chi
Apr 1, 2000·AIDS Patient Care and STDs·J Laurence
Jun 8, 2001·Journal of the National Cancer Institute·E A HollyJ M Palefsky
Feb 27, 1999·Current Opinion in Obstetrics & Gynecology·L KuhnT C Wright
May 10, 2001·Clinical Obstetrics and Gynecology·M A Young, R A Clark
May 10, 2001·Clinical Obstetrics and Gynecology·A P Korn
Mar 5, 2002·Sexually Transmitted Diseases·Giuseppe De PanfilisSevero Graifemberghi
Apr 3, 1998·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·J M PalefskyT M Darragh
Mar 18, 2008·Infectious Agents and Cancer·Maria Alice G GonçalvesEduardo Massad
Sep 13, 2000·Women & Health·M J Míguez-BurbanoM K Baum
Feb 7, 2003·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Ann B Williams
Nov 21, 2008·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Paulo GiraldoAna Katherine Gonçalves
May 16, 2007·Infectious Disease Clinics of North America·Daniel E Cohen, Kenneth H Mayer
Jun 2, 2000·Seminars in Cutaneous Medicine and Surgery·R A Johnson
Jan 16, 1998·Obstetrics and Gynecology Clinics of North America·A P Korn, P D Abercrombie
Apr 5, 2013·The American Journal of Surgical Pathology·Rajeev BalaTeri A Longacre
May 4, 2005·Memórias do Instituto Oswaldo Cruz·Alcina Frederica NicolMaria da Gloria Bonecini-Almeida
Oct 13, 2006·Human Molecular Genetics·Malin T EngelmarkUlf B Gyllensten
Mar 10, 2001·Clinical and Diagnostic Laboratory Immunology·M ScottA B Moscicki
May 2, 2017·Frontiers in Psychology·Michael H Pollak, J Ryan Hart
Aug 21, 2019·Frontiers in Oncology·Chenhao ZhouIan Hector Frazer
Dec 1, 1996·Obstetrics and Gynecology Clinics of North America·T C Wright, X W Sun

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.