Prevalence of Analgesic Use and Pain in People with and without Dementia or Cognitive Impairment in Aged Care Facilities: A Systematic Review and Meta-Analysis

Current Clinical Pharmacology
Edwin C K TanJ Simon Bell

Abstract

Pain is a frequent cause of discomfort and distress in residents in residential aged care facilities (RACFs). Despite the benefits of adequate pain management, there is inconsistency in the literature regarding analgesic use and pain in residents with dementia. The aim of this systematic review was to determine the prevalence of analgesic drug use among residents with and without dementia or cognitive impairment in RACFs. A systematic search of MEDLINE and EMBASE (inception to January 2014) was conducted using Medical Subject Headings and Emtree terms, respectively. Studies were included if they reported prevalence of analgesic use for residents both with and without dementia within the same study. Data extraction and quality assessment was performed independently by two investigators. Data on the prevalence of analgesic use, pain and painful conditions were extracted. Meta-analyses were performed using random effect models. The 7 included studies were of high quality (≥ 5 out of 7 on the adapted Newcastle-Ottawa Scale). Analgesic use in residents with and without dementia or cognitive impairment ranged from 20.2% to 61.2% and 38.8% to 79.6%, respectively. Paracetamol was the most prevalent analgesic in people with and without ...Continue Reading

Citations

Nov 3, 2015·Journal of the American Medical Directors Association·Brian LeungJ Simon Bell
Jun 14, 2015·European Journal of Clinical Pharmacology·Barbara Caecilia WimmerJ Simon Bell
Jun 18, 2016·Behavioural Neurology·Marina de TommasoMassimiliano Valeriani
Jul 12, 2016·Expert Review of Neurotherapeutics·Marina de TommasoMassimiliano Valeriani
May 4, 2017·Expert Opinion on Drug Metabolism & Toxicology·Emily ReeveSarah N Hilmer
Nov 8, 2017·Drugs -- Real World Outcomes·Natali JokanovicJ Simon Bell
Sep 25, 2018·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Yuta KuboShinichi Okada
Feb 7, 2019·International Journal of Geriatric Psychiatry·Laurna BullockPaul Campbell
Jun 8, 2019·International Journal of Geriatric Psychiatry·Tesfahun C EshetieLisa M Kalisch Ellett
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Sep 29, 2017·The Gerontologist·Staja Star Booker, Rashida D Booker
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Aug 22, 2017·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Ellen E LeeJeremy Hirst
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Apr 7, 2018·Research in Social & Administrative Pharmacy : RSAP·Julia Fiona-Maree Gilmartin-ThomasJohn McNeil

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