Prevalence of anti-A and anti-B hemolysis among blood group O donors in Lagos

Nigerian Journal of Clinical Practice
O A OyedejiA S Akanmu

Abstract

Group O donor blood is more readily available and is frequently used as universal red cell donor in our environment. The presence of hemolysins in the donors may however lead to hemolysis in the recipients. Attempts have been made to study the prevalence of hemolysins in various populations with results from our environment showing wide variation (20-80%). To determine the prevalence and titer of anti-A and anti B hemolysins among blood donors at the Lagos University Teaching Hospital and compare results with that obtained elsewhere. Determine if the practice of transfusion of group O blood to nongroup O recipients is permissible in this environment. Test for hemolysis was done using the standard tube method. Samples positive for hemolysis were then scored and titrated with the titers read visually and photometrically at 540 nm. Three hundred and fifty blood group O donors with age range 18-58 years and median age of 28 ΁ 8.4 years were enrolled in the study. The overall prevalence of anti-A and/or anti-B hemolysins obtained was 30.3%. Prevalence of anti-A and anti-B hemolysins only was 15.4% and 5.1% respectively whereas both anti-A and anti-B hemolysins were present in 9.7% donor samples. Though anti-A hemolysins were more pr...Continue Reading

Citations

Oct 23, 2015·Journal of Blood Transfusion·Alani Sulaimon AkanmuAnn Abiola Ogbenna
Mar 23, 2017·The Journal of Trauma and Acute Care Surgery·Yann DanielChristophe Martinaud
Sep 9, 2017·Journal of the Royal Army Medical Corps·Heidi DoughtyP Parker
Feb 8, 2018·Journal of Perinatology : Official Journal of the California Perinatal Association·R D ChristensenS J Ilstrup
Jul 7, 2020·JAMA Pediatrics·Francesca OkolieJon F Watchko

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