PMID: 2506955Oct 1, 1989Paper

Prevalence of antibodies to hepatitis C virus (HCV) in haemophiliacs

Blut
W SchrammF Deinhardt

Abstract

The prevalence of 1) hepatitis C virus (HCV), an agent likely to be responsible for parenterally transmitted hepatitis non-A, non-B, 2) hepatitis B virus (HBV) and 3) human immunodeficiency virus (HIV) infection was studied in 211 patients with clotting disorders (78% of the patients had residual factor activities of less than or equal to 2%). Of these patients 71% were positive for HBV markers and 44% for HIV markers. Using a new ELISA technique, 80% were anti-HCV-positive. The prevalence of anti-HCV was greater in patients with more severe clotting disorders and was related to the total amount of replacement therapy received; the prevalence was less in older patients. Seroconversion after a single exposure to dry heat-treated factor concentrates was documented in 3 patients 3-4 months after exposure.

Citations

Apr 1, 1997·Virchows Archiv : an International Journal of Pathology·E BierhoffJ Oldenburg
Aug 1, 1990·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·H RollagA Glomstein
Sep 1, 1990·Baillière's Clinical Gastroenterology·N Sheron, G J Alexander
Mar 29, 2001·Transfusion·J M SoucieUNKNOWN Hemophilia Surveillance System Project Investigators
Apr 1, 1990·Japanese Journal of Medical Science & Biology·S BoonmarT Miyamura
May 1, 1994·Transactions of the Royal Society of Tropical Medicine and Hygiene·M G SalehI G McFarlane
Feb 1, 1991·Annals of Hematology·P BaurD Roelcke
Jan 1, 1992·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·R VranckxG Thiers
Nov 1, 1991·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·P RautenbergG Loose
Apr 1, 1993·Australian and New Zealand Journal of Medicine·R P HardimanE J Gowans
Feb 1, 1994·Australian and New Zealand Journal of Medicine·D G WoodfieldM Mayumi
Jul 1, 1991·Infection·I KöksalH Köksal
Jan 1, 1996·Archives of Gerontology and Geriatrics·S UrsoF Rapisarda
Nov 9, 1990·Klinische Wochenschrift·M KieseU Bienzle
Apr 1, 1997·Kidney International·B J Pereira, A S Levey
Jan 1, 1991·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·J Abb
Jan 1, 1995·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·B WeberH W Doerr
May 1, 1992·Journal of Hepatology·T LaskusJ Slusarczyk
Apr 1, 1996·The British Journal of Oral & Maxillofacial Surgery·K M RoyG D Lowe
Nov 1, 1991·Journal of Hepatology·S DittmannF Deinhardt
Mar 1, 1990·Revue française de transfusion et d'hémobiologie : bulletin de la Société nationale de transfusion sanguine·A M Couroucé
Jul 1, 1991·Journal of Hepatology·T H WangD S Chen
Feb 1, 1993·Journal of Hepatology·M S KhurooG N Yattoo
Sep 1, 1992·The Journal of Infection·R P Brettle
Jan 1, 1991·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·P CoursagetP Le Cann
Sep 2, 1998·American Journal of Hematology·H A Hill, S F Stein

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.