Prevalence of Atopic Dermatitis and Pattern of Drug Therapy in Malaysian Children

Dermatitis : Contact, Atopic, Occupational, Drug
Yi-Yeong GohYik Ling Chew

Abstract

Atopic dermatitis (AD) is a chronic relapsing, noncontagious skin inflammation characterized by dry skin and itch. Mutation in filaggrin gene leads to defective skin barrier, allowing entry of allergen and eliciting immunological response. The aims of this study were to investigate the prevalence of AD in Malaysian children and to understand the pattern of drug therapy. Such information could be useful to establish the relationship between ethnicity and family history of atopy and the development of associated signs and symptoms. A cross-sectional survey was conducted among children attending kindergartens and nurseries. Standardized questionnaires were filled out by parents. Overall prevalence of AD was 13.4%. Of 384 participants recruited, the highest prevalence was observed in males, Malays, participants younger than 2 years, and those with atopic background such as asthma, hay fever, and family history of atopic diseases. Calamine and white soft paraffin were the preferred choice of nonprescription drugs, whereas topical hydrocortisone seemed to be the preferred choice of prescription drug in the management of AD. The overall prevalence is comparable to that reported in the International Study of Asthma and Allergies in Chi...Continue Reading

References

Feb 1, 1995·Journal of the American Academy of Dermatology·H C WilliamsP G Burney
Nov 1, 1993·Clinical and Experimental Dermatology·R B Jaafar, J H Pettit
Jan 1, 1994·Journal of the American Academy of Dermatology·J KayA G Jaron
May 1, 1996·Journal of the American Academy of Dermatology·F Schultz LarsenA Svensson
Apr 1, 1997·The Journal of Allergy and Clinical Immunology·R J RonaS Chinn
Sep 27, 2000·Journal of the American Academy of Dermatology·D LaughterJ M Hanifin
Jun 29, 2002·Archives of Disease in Childhood·A SherriffUNKNOWN Alspac Study Team
Sep 6, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M BöhmeC F Wahlgren
Feb 28, 2004·Journal of the American Academy of Dermatology·Mohamed A Ben-GashirRoderick J Hay
Sep 24, 2004·Archives of Disease in Childhood·N Wadonda-KabondoUNKNOWN ALSPAC Study Team
Apr 13, 2005·Respirology : Official Journal of the Asian Pacific Society of Respirology·B S QuahA R Mazidah
May 27, 2005·Pediatric Dermatology·Christie L CarrollJaneen C Manuel
Jun 3, 2005·The New England Journal of Medicine·Hywel C Williams
Jul 4, 2006·The Journal of Allergy and Clinical Immunology·Torsten ZuberbierJan C Simon
Dec 13, 2006·Clinical & Developmental Immunology·Agnes KuhnyarLajos Kosa
Feb 1, 2007·The British Journal of Dermatology·J M HarrisP Cullinan
Feb 5, 2008·The British Journal of Dermatology·E E A BrenninkmeijerPh I Spuls
Jun 24, 2008·The Journal of Allergy and Clinical Immunology·John A BurgessE Haydn Walters
Aug 27, 2010·The Journal of Investigative Dermatology·Tatyana E ShawEric L Simpson
Jul 20, 2011·Seminars in Cutaneous Medicine and Surgery·Judith HongMartin Steinhoff
Oct 2, 2012·The Journal of Allergy and Clinical Immunology·John L HopperShyamali C Dharmage
Nov 16, 2012·World Journal of Pediatrics : WJP·Zbigniew Samochocki, Jowita Dejewska
Jan 8, 2013·The Journal of Dermatology·Diana RubelUNKNOWN Asia-Pacific Consensus Group for Atopic Dermatitis
Jan 23, 2015·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·W Peng, N Novak

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Related Papers

The Journal of Allergy and Clinical Immunology
Jonathan I SilverbergTamar A Smith-Norowitz
The Journal of Allergy and Clinical Immunology
Michael D HowellDonald Y M Leung
The Journal of Allergy and Clinical Immunology
Michael D HowellDonald Y M Leung
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
O S Von EhrensteinR von Kries
© 2022 Meta ULC. All rights reserved