Prevalence of bovine trypanosomosis and trypanocidal drug sensitivity studies on Trypanosoma congolense in Wolyta and Dawero zones of southern Ethiopia

Veterinary Parasitology
A MirukA K Basu

Abstract

Cross-sectional studies were conducted in tsetse and non-tsetse-controlled areas of the Southern Nation Nationalities and Peoples Regional State (SNNPRS) of Ethiopia to determine the prevalence of bovine trypanosomosis as well as drug sensitivity tests on Trypanosoma congolense in both naturally and experimentally infected cattle and mice, respectively. A total trypanosome prevalence of 4.8% (95% CI: 1.8-7.5) and 20.4% (95% CI: 14-26.8) were recorded in the tsetse-controlled study area of Humbo district and the non-tsetse-controlled area of Mareka district, respectively, indicated statistically significant difference between the two areas (P<0.001). The mean PCV value for Humbo and Mareka was 26.2 (95%: 25.7-26.7) and 22.7 (95% CI: 22.1-23.3), respectively, which were also statistically significant (P<0.001). The prophylactic activity of isometamidium chloride (ISMM) was observed in Humbo on nine naturally positive zebu cattle. Breakthrough infections were recorded in (6/9) 66.7% of the cases in less than 5 weeks. A qualitative assay on mice was conducted on two T. congolense isolates obtained from the breakthrough cases with ranges of doses of ISMM and diminazene diaceturate (DA). Thereafter the mice were followed for relapse ...Continue Reading

References

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Citations

Feb 17, 2015·The Onderstepoort Journal of Veterinary Research·Kumela LelisaDesie Sheferaw
Feb 17, 2015·The Onderstepoort Journal of Veterinary Research·Japhta M MokoeleFolorunso O Fasina
Jan 19, 2013·The Onderstepoort Journal of Veterinary Research·Wagari TafeseTewodros Fentahun
Jun 26, 2010·Tropical Animal Health and Production·Abebayehu Tadesse, Biniam Tsegaye
Oct 31, 2012·Tropical Animal Health and Production·Albert SoudréJohann Sölkner
Mar 12, 2016·Parasites & Vectors·Samson LetaMelkamu Bezie
Dec 19, 2012·Research in Veterinary Science·Michael I TakeetIkhide G Imumorin
Sep 13, 2018·PLoS Neglected Tropical Diseases·Gebrekrustos MekonnenHadush Birhanu
Dec 22, 2017·Parasitology Research·Fernando Chanisso MulandaneLuis Neves
Mar 9, 2021·Veterinary Parasitology : Regional Studies and Reports·Efrem DegnehTekalegn Desta

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