Prevalence of carotid plaque stenosis after head and neck radiotherapy - an observational study of 156 survivors

VASA. Zeitschrift für Gefässkrankheiten
Marie-Luise ValentinNils Kucher

Abstract

Background: Radiotherapy for head and neck cancer (HNC) represents a well-known predisposing factor for asymptomatic carotid artery lesions and acute cerebrovascular accidents. Our aim is to provide contemporary estimates on the prevalence, severity, and characteristics of carotid artery lesions in HNC survivors. Patients and methods: We prospectively included HNC patients who underwent radiotherapy and were free from the disease at the time of duplex ultrasound evaluation. Patients were re-contacted telephonically and those who agreed to participate were invited for an ambulatory visit when the investigators collected clinical information and performed duplex ultrasound examination based on a predefined protocol. Results: A total of 156 patients were included and underwent duplex ultrasound examination after a mean of 65.2 months from the last session of radiotherapy. A total of 36 patients (23.1%) had normal carotid arteries; mild, non-stenotic lesions were observed in 49.4% (n = 77) of patients; severe stenotic plaques were found in 27.5% (n = 43) of patients. One patient found with an asymptomatic occlusion of the left ICA. The prevalence of major cardiovascular risk factors and high radiation dose increased proportionally ...Continue Reading

References

Apr 16, 1998·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·A H Friedlander, M August
Nov 18, 2000·The Laryngoscope·K MuzaffarW H Baker
Mar 27, 2002·Cerebrovascular Diseases·W W M LamC Metreweli
May 7, 2002·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M HalakR Karmeli
Dec 6, 2003·JAMA : the Journal of the American Medical Association·Matthew C HullNancy Price Mendenhall
Jan 27, 2004·Journal of Vascular Surgery·Stephen W K ChengLisa L H Wu
May 3, 2005·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Lucille D A DorresteijnWillem Boogerd
Jul 28, 2009·Journal of Vascular Surgery·Yeu-Jhy ChangShan-Jin Ryu
Apr 24, 2010·Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie·C ArningM Görtler
Aug 6, 2011·Stroke; a Journal of Cerebral Circulation·Chris PlummerStephen J Read
Mar 23, 2012·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M FokkemaG J de Borst
Sep 5, 2012·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·A GrecoM de Vincentiis
Sep 21, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Dorothy M GujralChristopher M Nutting
Nov 6, 2013·Clinical Oncology : a Journal of the Royal College of Radiologists·D M GujralC M Nutting
Oct 23, 2014·Interventional Neurology·Jiaping Xu, Yongjun Cao
Dec 30, 2014·VASA. Zeitschrift für Gefässkrankheiten·Christoph ThalhammerBeatrice R Amann-Vesti
Feb 29, 2016·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Josep M BorrasCai Grau
Nov 7, 2016·Clinical Oncology : a Journal of the Royal College of Radiologists·D M GujralC M Nutting
Jan 18, 2018·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Shuichi TonomuraNobuyuki Takahashi
May 1, 2018·Oral Oncology·David J CarpenterDavid M Brizel
Apr 3, 2019·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Wang LiaoJun Liu
Jun 22, 2019·Current Diabetes Reports·Ram JagannathanK M Venkat Narayan

❮ Previous
Next ❯

Citations

Jun 10, 2021·VASA. Zeitschrift für Gefässkrankheiten·Veronica Fernández-AlvarezFernando López Alvarez

❮ Previous
Next ❯

Methods Mentioned

BETA
imaging techniques

Software Mentioned

StatView

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Rinsho byori. The Japanese journal of clinical pathology
Toshiyasu Ogata, Hirofumi Shimada
Interventional Neurology
Andreas Harloff
© 2021 Meta ULC. All rights reserved